Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Capital Based Sustainability Indicators as a Possible Way for Measuring Agricultural Sustainability [PDF]
This paper takes the capital based approach to sustainability and applies this to examine the sustainability of different farming methods. The capital based approach argues that for future generations to be as well off as the present than the capital ...
Saunders, Caroline M. +2 more
core +1 more source
Attitudes and barriers of dental educators toward integrated environmentally sustainable oral health education in Saudi Arabia. [PDF]
Binduhayyim RIH.
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Nutrition Literacy, Hydration Awareness and Food Label Use in School Populations: A Cross-Sectional Study of Students and Teachers Across European Contexts. [PDF]
Coradduzza D +11 more
europepmc +1 more source
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Improving organizational sustainability using a quality perspective [PDF]
This article derives lessons from the quality approach for further developing the organizational sustainability approach. Taking a responsibility perspective on organizational sustainability, four issues emerge that need to be resolved, i.e.
Broekhuis, Manda, Vos, Janita F.J.
core +1 more source
Optimizing solid waste, effluents and blockchain technology efforts towards a sustainable palm oil stochastic supply chain model. [PDF]
Peter John A, Mishra U.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Enhancing competitiveness in accommodation management: sustainability-led strategies for tourism and event destinations. [PDF]
Atoevna TS +3 more
europepmc +1 more source

