Results 71 to 80 of about 1,632,943 (344)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Data in BriefLakes can undergo rapid changes that are not captured during traditional, discrete sampling campaigns. Sensor-based data provide opportunities to understand these rapid changes in lakes.
Helen Baulch +7 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
RETRACTED: Song et al. Spatial–Temporal Characteristics and Determinants of Digital Divide in China: A Multivariate Spatial Analysis. Sustainability 2019, 11, 4529 [PDF]
, 2022 Zhouying Song +3 more
openalex +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Good Governance: A Framework for Implementing Sustainable Land Management, Applied to an Agricultural Case in Northeast-Brazil [PDF]
, 2019 Land management needs to cope with persistent environmental and societal changes. This requires functional governance systems. The purpose of this research is to develop a good governance framework for the implementation of sustainable land management ...
Guschal, Maike +4 more
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Applied Rheology, 2022 The viscosities of poly(3-hydroxybutyrate) (PHB) with mixed tacticities were determined as functions of temperature and shearing rate via plate–plate viscosimetry, and fitted by a combined Herschel–Bulkley–Cross–Doolittle model while applying Carvalho et
Van Opdenbosch Daniel +3 more
doaj +1 more source
Architectural and Management Strategies for the Design, Construction and Operation of Energy Efficient and Intelligent Primary Care Centers in Chile [PDF]
, 2019 Primary care centers are establishments with elevated social relevance and high operational energy consumption. In Chile, there more than 628 family healthcare centers (CESFAM) have been built in the last two decades and with plans for hundreds more in
Bobadilla, Ariel +4 more
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