Results 111 to 120 of about 17,398,133 (240)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
14th Annual microprogramming workshop : October 12-15, 1981, Chatham, Massachusetts.
October 12-15, 1981, Palo Alto ...
Annual microprogramming workshop14thOctober 12-15, 1981Chatham, Mass.
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Στοιχείο: EλλάδαΣτοιχείο: ΆγνωστοςΣτοιχείο: Βρισκόταν στο Λιτόχωρο το 1786, όπως αναφέρεται στην "Ακολουθία του ετεροφθάλμου και αντιχρίστου Χριστοδούλου του εξ Ακαρνανίας"
Αναστάσιος (12)
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
CK-12 is comprised of free, open access resources for both teachers and students including online textbooks, lesson plans, worksheets, and much more. The site has both a student and teacher view, and on the homepage, subjects are broken down by category.
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A New Approach to the Analysis of Dissolved Gases Using Passive Samplers, With Portable Mass Spectrometry and Gas Chromatography Techniques. [PDF]
Picard A +4 more
europepmc +1 more source

