Results 181 to 190 of about 106,831 (296)

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun   +7 more
wiley   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li   +10 more
wiley   +1 more source

Amino Acid Based Ionic Liquids as Co-Catalyst for Co2 Electrochemical Reduction

open access: yes
Carbon Capture Utilization and Storage (CCUS) provides key contribution in tackling the emission of CO2 in align of the Sustainable Development Goal (SDG 13 Climate Action) to achieve net zero carbon emission by ...
SEENIVASAGAM, KAVAN
core  

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

open access: yesAdvanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang   +18 more
wiley   +1 more source

The role of atmospheric CO2 in controlling patterns of sea surface temperature change during the Pliocene

open access: yes
Haywood, AM   +7 more
core   +1 more source

RU Department of Geography

open access: yes
Department of Geography Department of Geography Foundational Sustainable Development Goals (SDGs) SDG 13 Climate Action Foundational Sustainable Development Goals (SDGs) SDG 14 Life below Water Foundational Sustainable Development Goals (SDGs) SDG

core  

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