Results 61 to 70 of about 1,309,182 (315)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Introduction to Ethics: An Open Educational Resource, collected and edited by Noah Levin [PDF]
, 2019 Collected and edited by Noah Levin Table of Contents: UNIT ONE: INTRODUCTION TO CONTEMPORARY ETHICS: TECHNOLOGY, AFFIRMATIVE ACTION, AND IMMIGRATION 1 The “Trolley Problem” and Self-Driving Cars: Your ...
Davies, Benjamin +11 more
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Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Development of criteria and procedures for the evaluation of the European Action Plan for Organic Agriculture [PDF]
, 2008 This final report provides a synthesis of the results of the EU-funded ORGAP project, with the title “European Action Plan of Organic Food and Farming - Development of criteria and procedures for the evaluation of the EU Action Plan for Organic ...
Dabbert, Stephan +5 more
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FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Staying on Track from Paris: Advancing the Key Elements of the Paris Agreement [PDF]
, 2016 The Paris Agreement adopted in December 2015 provides essential building blocks for universal action to address climate change. Now, much work is needed to breathe life into the provisions and commitments of the Agreement in order to realize the globally
Cynthia Elliott +8 more
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Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
The effect of temperature on the Emission Factor of air emissions from pyrolysis of used tyres
Results in EngineeringUsed tyres pyrolysis is an efficient solid waste management strategy for used tyres and a growing method of fuel oil production. However, the impact of air emissions associated at different temperature on ambient air quality has not been determined.
Omotayo Seriki +3 more
doaj +1 more source
Climate Action In Megacities 3.0 [PDF]
, 2015 "Climate Action in Megacities 3.0" (CAM 3.0) presents major new insights into the current status, latest trends and future potential for climate action at the city level. Documenting the volume of action being taken by cities, CAM 3.0 marks a new chapter
A. Mark Fendrick +19 more
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