Results 21 to 30 of about 123,676 (195)

Underwater Fish Detection with Weak Multi-Domain Supervision

open access: yes, 2019
Given a sufficiently large training dataset, it is relatively easy to train a modern convolution neural network (CNN) as a required image classifier. However, for the task of fish classification and/or fish detection, if a CNN was trained to detect or ...
Bradley, Michael   +5 more
core   +1 more source

Hydraulic Abrasion-Resistant Elastic Epoxy Resin Materials

open access: yesAdvances in Materials Science and Engineering, 2019
The abrasion of hydraulic concrete structures caused by the washing action of flowing water is a common problem and cannot be solved by simply increasing the strength of the concrete.
Liqun Xu, Kai Zhang, Yanhui Liu
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Mapping of K-12 science and mathematics curriculum against sustainable development goals and addressing sustainability gap

open access: yesCogent Education
This paper uncovers the sustainability content in the science and mathematics curriculum of Qatar’s K-12 public school system. It focuses on mapping the curriculum standards of both subjects against sustainable development goals (SDGs) and identifying ...
Ziad Said   +4 more
doaj   +1 more source

Plastron respiration using commercial fabrics [PDF]

open access: yes, 2014
A variety of insect and arachnid species are able to remain submerged in water indefinitely using plastron respiration. A plastron is a surface-retained film of air produced by surface morphology that acts as an oxygen-carbon dioxide exchange surface ...
Cassie   +24 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Underwater Noise from Arctic Shipping: Impacts, Regulations and Recommendations [PDF]

open access: yes, 2017
Marine mammals, including whales, walrus, and seals, rely heavily on sounds for survival. The Arctic soundscape has long been shaped by their clicks and calls.

core  

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

open access: yesAdvanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers   +3 more
wiley   +1 more source

Spectral signatures of photosynthesis II: coevolution with other stars and the atmosphere on extrasolar worlds

open access: yes, 2007
As photosynthesis on Earth produces the primary signatures of life that can be detected astronomically at the global scale, a strong focus of the search for extrasolar life will be photosynthesis, particularly photosynthesis that has evolved with a ...
Antígona Segura   +12 more
core   +2 more sources

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

open access: yesAdvanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li   +10 more
wiley   +1 more source

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