Results 51 to 60 of about 21,101 (137)
Exploring Costa Rica's fungal trends: Insights from digitized specimens
Fungi are essential to tropical ecosystems but remain largely absent from conservation agendas. By analyzing over 78,000 fungal records from Costa Rica—a globally recognized biodiversity hotspot—this study reveals key patterns in fungal diversity, distribution, and seasonality.
Melissa Mardones +2 more
wiley +1 more source
Shaping expectations, losing flexibility: A study of CEO promises as strategic communication tools
Abstract Research Summary CEO promises are powerful but understudied communication tools. We develop a dual‐mechanism framework theorizing that while CEO promises elevate stakeholder expectations, they simultaneously constrain strategic flexibility. We argue that CEO promise‐making is shaped by two competing pressures: making more promises when the ...
Majid Majzoubi +2 more
wiley +1 more source
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo +19 more
wiley +1 more source
Mitigating disparities in diagnosis of dementia
Abstract The field of Alzheimer's disease and related dementias (AD/ADRD) is undergoing a transformative shift with a better understanding of disease biology, biomarker‐based diagnostics, and disease‐modifying therapies. Yet, these advancements risk exacerbating existing disparities in diagnosis and care.
Lycia Tramujas Vasconcellos Neumann +36 more
wiley +1 more source
This study detected the diet and gut microbiota of great bustards and common cranes in the wintering duration in the Yellow River Wetlands of Inner Mongolia using high‐throughput sequencing technology. This study indirectly indicated that great bustards and common cranes are well‐adapted to the environment of the Yellow River Wetlands during the ...
Li Gao +4 more
wiley +1 more source
Pubertal timing and incident uterine cancer in the Sister Study cohort
What's new? Younger age at menarche is an established risk factor for uterine cancer. Age at onset of breast development (thelarche), the earliest marker of pubertal estrogen exposure unopposed by progesterone, may also be relevant to uterine cancer risk, but this association has not been explored. Using data from the US prospective Sister Study cohort,
Ariayana N. Harrell +4 more
wiley +1 more source
Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge +9 more
wiley +1 more source
Homo luzonensis and the role of homoplasy in the morphology of hominin insular species
Abstract Homo luzonensis lived during the upper Pleistocene in the northern Philippines, east of the Wallace line. The few specimens attributed to this species show a mosaic of plesiomorphies for the genus Homo and apomorphies found in upper Pleistocene Homo species.
Pierre Gousset +4 more
wiley +1 more source
ABSTRACT Aims There is ongoing uncertainty about whether initiating sodium–glucose co‐transporter 2 inhibitor (SGLT‐2i) therapy in individuals with type 2 diabetes (T2D) who have elevated baseline HbA1c levels may lead to an additive or potentially synergistic increase in the risk of diabetic ketoacidosis (DKA). This systematic review and meta‐analysis
Samuel Seidu +3 more
wiley +1 more source
The impact of accumulating immune adaptation in circulating strains of HIV‐1
Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi +7 more
wiley +1 more source

