Results 11 to 20 of about 63 (63)

The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis

open access: yesVeterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger   +4 more
wiley   +1 more source

The maximal unipotent finite quotient, unusual torsion in Fano threefolds, and exceptional Enriques surfaces [PDF]

open access: yesÉpijournal de Géométrie Algébrique, 2020
We introduce and study the maximal unipotent finite quotient for algebraic group schemes in positive characteristics. Applied to Picard schemes, this quotient encodes unusual torsion.
Andrea Fanelli, Stefan Schröer
doaj   +1 more source

Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus

open access: yesVeterinary Dermatology, Volume 32, Issue 6, Page 681-e182, December 2021., 2021
Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck   +6 more
wiley   +1 more source

Nonemptiness of severi varieties on enriques surfaces

open access: yesForum of Mathematics, Sigma, 2023
Let $(S,L)$ be a general polarised Enriques surface, with L not numerically 2-divisible. We prove the existence of regular components of all Severi varieties of irreducible nodal curves in the linear system $|L|$ , that is, for any number of
Ciro Ciliberto   +3 more
doaj   +1 more source

A masked, randomised clinical trial evaluating the efficacy and safety of lokivetmab compared to saline control in client‐owned dogs with allergic dermatitis

open access: yesVeterinary Dermatology, Volume 32, Issue 5, Page 477-e131, October 2021., 2021
Background – Interleukin (IL)‐31 is an important mediator in canine atopic dermatitis (cAD) and also may be dysregulated in other allergic diseases. Hypothesis/Objectives – To demonstrate the efficacy and safety of lokivetmab (canine anti‐IL‐31 monoclonal antibody) for treatment of pruritus associated with allergic dermatitis in dogs.
Leen Van Brussel   +4 more
wiley   +1 more source

The Kodaira dimension of some moduli spaces of elliptic K3 surfaces

open access: yesJournal of the London Mathematical Society, Volume 104, Issue 1, Page 269-294, July 2021., 2021
Abstract We study the moduli spaces of elliptic K3 surfaces of Picard number at least 3, that is, U⊕⟨−2k⟩‐polarized K3 surfaces. Such moduli spaces are proved to be of general type for k⩾220. The proof relies on the low‐weight cusp form trick developed by Gritsenko, Hulek and Sankaran.
Mauro Fortuna, Giacomo Mezzedimi
wiley   +1 more source

Efficacy and safety of 0.0584% hydrocortisone aceponate topical spray and systemic oclacitinib combination therapy in dogs with atopic dermatitis: a randomized, double‐blinded, placebo‐controlled trial

open access: yesVeterinary Dermatology, Volume 32, Issue 2, Page 119-e25, April 2021., 2021
Background – Oclacitinib is an effective systemic therapy for dogs with atopic dermatitis (AD). Few studies have evaluated concurrent topical treatment with oclacitinib in dogs. Objectives – To evaluate the efficacy and safety of combination therapy of oclacitinib and 0.0584% hydrocortisone aceponate (HCA) spray in dogs with AD.
Junko Takahashi   +9 more
wiley   +1 more source

Clinical efficacy of spray‐based heat‐treated lactobacilli in canine atopic dermatitis: a preliminary, open‐label, uncontrolled study

open access: yesVeterinary Dermatology, Volume 32, Issue 2, Page 114-e23, April 2021., 2021
Background – Canine atopic dermatitis (cAD) is a common inflammatory and pruritic skin disease, with various treatment options. The use of topical products containing natural ingredients has proven increasingly popular. Objective – To evaluate the effects of a spray solution containing heat‐killed Lactobacillus rhamnosus and L. reuteri, on the clinical
Domenico Santoro   +3 more
wiley   +1 more source

Q_l-cohomology projective planes and singular Enriques surfaces in characteristic two [PDF]

open access: yesÉpijournal de Géométrie Algébrique, 2019
We classify singular Enriques surfaces in characteristic two supporting a rank nine configuration of smooth rational curves. They come in one-dimensional families defined over the prime field, paralleling the situation in other characteristics, but ...
Matthias Schütt
doaj   +1 more source

Differential geometric global smoothings of simple normal crossing complex surfaces with trivial canonical bundle

open access: yesComplex Manifolds, 2023
Let XX be a simple normal crossing (SNC) compact complex surface with trivial canonical bundle which includes triple intersections. We prove that if XX is dd-semistable, then there exists a family of smoothings in a differential geometric sense. This can
Doi Mamoru, Yotsutani Naoto
doaj   +1 more source

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