Results 21 to 30 of about 6,762,275 (240)

Metformin - An Antidiabetic Drug With Anti-aging, Cardioprotective And Potential Anti-cancer Properties

Journal of Education, Health and Sport
Introduction: This review aims to examine the role of metformin, a widely used oral antihyperglycemic agent, and its emerging potential cardioprotective, anticancer, and anti-aging effects.
Magdalena Jabłonowska, Paulina Grzeszczuk, Aleksandra Kaczmarek, Wojciech Kaczmarek, Magdalena Krakowiak   +4 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Explaining and forecasting interannual variability in the flow of the Nile River [PDF]

Hydrology and Earth System Sciences, 2015
This study analyzes extensive data sets collected during the twentieth century and defines four modes of natural variability in the flow of the Nile River, identifying a new significant potential for improving predictability of floods and droughts ...
M. S. Siam, E. A. B. Eltahir
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

The Aortic Prosthesis and Aortic Valve Bioprosthesis Trombosis as a Late Complication in Patients after the Bentall Procedure Followed by a Valve-in-Valve Transcatheter Aortic Valve Implantation

Diagnostics
Background: Valve-in-Valve (ViV) transcatheter aortic valve implantation (TAVI) has emerged as a viable therapeutic option for structural valve degeneration following surgical aortic valve replacement (SAVR) or prior TAVI.
Paweł Muszyński, Oliwia Grunwald, Maciej Południewski, Paweł Kralisz, Szymon Kocańda, Tomasz Hirnle, Sławomir Dobrzycki, Marcin Kożuch   +7 more
doaj   +1 more source

Kappa Free Light Chains and IgG Combined in a Novel Algorithm for the Detection of Multiple Sclerosis

Brain Sciences, 2020
Background: It is well known that the cerebrospinal fluid (CSF) concentrations of free light chains (FLC) and immunoglobulin G (IgG) are elevated in multiple sclerosis patients (MS).
Monika Gudowska-Sawczuk, Joanna Tarasiuk, Alina Kułakowska, Jan Kochanowicz, Barbara Mroczko   +4 more
doaj   +1 more source

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

Lo llaman Democracia, pero ¿a qué? Tres perspectivas sobre el significado de la Democracia en tiempos de crisis y protesta

Relaciones Internacionales, 2013
Review-Essay sobre las siguientes obras: • COLECTIVO NOVECENTO (VV. AA), Lo llamaban democracia. De la crisis económica al cuestionamiento de un régimen político, Icaria, Barcelona, 2013, ps.
Ramón ESPINAR MERINO
doaj  

The Expression of Bcl-2 and BID in Gastric Cancer Cells

Journal of Immunology Research, 2014
Background. Bcl-2 and BID play a major role in the process of apoptosis and their dysfunction underlies carcinogenesis. The study objective was to assess the expression of Bcl-2 and BID in gastric cancer cells in correlation with chosen ...
Mariusz Gryko, Anna Pryczynicz, Konrad Zareba, Bogusław Kędra, Andrzej Kemona, Katarzyna Guzińska-Ustymowicz   +5 more
doaj   +1 more source