Results 171 to 180 of about 36,481,988 (264)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Multiband Optical Physical Unclonable Functions Based on Mixed-Phase Multilevel Emissive Perovskites. [PDF]

Adv Sci (Weinh)
Park S, Kim J, Boo J, Kim G, Yoon J, Bae J, Cho S, Park W, Park DH, Im H.   +9 more
europepmc   +1 more source

AFO 150

Drugs in R & D, 2002
openaire   +2 more sources

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Ultrasonic-Assisted pulse electrodeposition of Ni-P/Graphene oxide composite Coatings: Effect of acoustic energy on Microstructure, Wear, and corrosion. [PDF]

Ultrason Sonochem
Köse M, Tan S, Çetinkaya B, Alaf M, Gültekin D, Algül H, Akbulut H, Uysal M.   +7 more
europepmc   +1 more source

Potential effect of human chorionic gonadotropin‐induced extracellular vesicle RNAs on mouse ovarian granulosa cells

FEBS Open Bio, EarlyView.
To mimic the LH action in the ovary, granulosa‐cell and mouse models were stimulated by hCG, which changed RNA profiles within extracellular vesicles (EVs), and potentially hCG‐responsive EV RNAs increased the number of recipient ovarian cells. EV‐associated RNAs are potential intermediaries of hCG signaling.
Natchanok Puangjit, Nobuhiko Takahashi, Yuki Maruyama, Shota Mayama, Katsueki Ogiwara, Chika Fujimori, Atsushi P. Kimura   +6 more
wiley   +1 more source

Dual-mode SOX2 regulation by miR-150 via mRNA suppression and autophagy controls stem cell fate. [PDF]

Signal Transduct Target Ther
Zhen X, Koh H, Lee DS, Huh JW, Hong SH, Kim TD, Lee JH.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source