Results 11 to 20 of about 14,106,984 (307)

Targeting carcinoembryonic antigen-expressing tumors using a novel transcriptional and translational dual-regulated oncolytic herpes simplex virus type 1

open access: yesMolecular Therapy: Oncolytics, 2023
VG2025 is a recombinant oncolytic herpes simplex virus type 1 (HSV-1) that uses transcriptional and translational dual regulation (TTDR) of critical viral genes to enhance virus safety and promote tumor-specific virus replication without reducing ...
Dmitry V. Chouljenko   +10 more
doaj   +1 more source

Interplay of Precursor and Plasma for The Deposition of HfO2 via PEALD: Film Growth and Dielectric Properties

open access: yesAdvanced Materials Interfaces, 2023
HfO2 thin films are appealing for microelectronic applications such as high‐κ dielectric layers, memristors, and ferroelectric memory devices. To fulfill the different requirements of each application, the properties of the deposited material need to be ...
Florian Preischel   +6 more
doaj   +1 more source

Nickel(II)-catalysed oxidative guanine and DNA damage beyond 8-oxoguanine [PDF]

open access: yes, 2007
Oxidative DNA damage is one of the most important and most studied mechanisms of disease. It has been associated with a range of terminal diseases such as cancer, heart disease, hepatitis, and HIV, as well as with a variety of everyday ailments.
Kelly, Michele C.   +3 more
core   +1 more source

Cell-derived Extracellular Matrix as maintaining Biomaterial for adipogenic differentiation

open access: yesCurrent Directions in Biomedical Engineering, 2020
The extracellular matrix (ECM) naturally surrounds cells in humans, and therefore represents the ideal biomaterial for tissue engineering. ECM from different tissues exhibit different composition and physical characteristics.
Kluger Petra J.   +3 more
doaj   +1 more source

Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice

open access: yesNature Communications, 2021
The CNS has limited ability to regenerate following injury, Here, the authors show that a single injection of AAV-hyper-interleukin-6 in the sensory motor cortex results in corticospinal and raphe spinal tracts regeneration in the injured spinal cord as ...
Marco Leibinger   +5 more
doaj   +1 more source

Flows on scales of 150 Mpc? [PDF]

open access: yes, 1998
We investigate the reality of large-scale streaming on scales of up to 150 Mpc using the peculiar motions of galaxies in three directions. New R-band CCD photometry and spectroscopy for elliptical galaxies is used.
G. Wegner   +7 more
core   +3 more sources

Rietveld Quantitative Phase Analysis of Oil Well Cement: in Situ Hydration Study at 150 Bars and 150 °C [PDF]

open access: yes, 2019
Oil and gas well cements are multimineral materials that hydrate under high pressure and temperature. Their overall reactivity at early ages is studied by a number of techniques including through the use of the consistometer.
Cuesta-Garcia, Ana Maria   +5 more
core   +6 more sources

How user behaviour affects emissions and costs in residential energy systems—The impacts of clothing and thermal comfort

open access: yesEnvironmental Research Communications, 2023
To mitigate climate change, energy systems must be decarbonised. Human behaviour affects energy systems on residential scales through technology adoption and use, but is often neglected in models for analysing energy systems.
David Huckebrink   +2 more
doaj   +1 more source

Synthesis, Crystal and Electronic Structures of a Thiophosphinoyl‐ and Amino‐Substituted Metallated Ylide

open access: yesChemistryOpen, 2021
Invited for this month's cover is the group of Viktoria H. Gessner at the Ruhr‐University in Bochum (Germany). The cover shows the structure of the newly reported, isolated metallated ylide.
Mike Jörges   +6 more
doaj   +2 more sources

Unveiling Ruthenium(II) Diazadienyls for Gas Phase Deposition Processes: Low Resistivity Ru Thin Films and Their Performance in the Acidic Oxygen Evolution Reaction

open access: yesAdvanced Materials Interfaces, 2022
Two novel ruthenium complexes belonging to the Ru(II)(DAD)(Cym) (DAD = diazadienyl) (Cym = cymene) compound family are introduced as promising precursors.
David Zanders   +12 more
doaj   +1 more source

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