Results 91 to 100 of about 4,477 (209)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
The aim of the study was to assess the position of Polish agriculture in the European Union (EU) regarding land and labour productivity. The study period was from 2007 to 2021, realised using the EUROSTAT database.
Zakrzewska, Aneta, Nowak, Anna
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, 1975 S\u142owa kluczowe: Jan \u141aski (1456-1531); Sachsenspiegel \u2013 przek\u142ady \u142aci\u144skie; prawo \u2013 Niemcy \u2013 15-16 w.; prawo \u2013 Polska \u2013 15-16 w.; prawo niemieckie w Polsce; prawo \u2013 Polska \u2013 Niemcy \u2013 \u17ar ...
Rymaszewski, Zygfryd
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Tendencje rozwojowe gospodarki polskiej [PDF]
, 2012 Zdigitalizowano i udostępniono w ramach projektu pn. Rozbudowa otwartych zasobów naukowych Repozytorium Uniwersytetu w Białymstoku, dofinansowanego z programu „Społeczna odpowiedzialność nauki” Ministra Edukacji i Nauki na podstawie umowy SONB/SP/512497 ...
Meredyk, Kazimierz
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FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
\u15amiech w czasach ostatecznych: tematyka religijna w \u201eFiglikach\u201d Miko\u142aja Reja
, 2013 S\u142owa kluczowe: Miko\u142aj Rej (1505-1569); literatura renesansowa w Polsce; reformacja \u2013 Niemcy i Polska (16 w.); \u15bmiech w kulturze; facecje i figliki w literaturze ...
St\u119pie\u144, Pawe\u142
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