Results 151 to 160 of about 267,584 (295)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

New Taxa of Filamentous Cyanobacteria from Freshwater Habitats in China: Description of Neoleptolyngbya gen. nov. with Two Species, and Pseudoleptolyngbya wuhanensis sp. nov. [PDF]

Microorganisms
Cai F, Chen J, Li S, Li X, Li R.
europepmc   +1 more source

Term 16

Medical Mycology Journal, 2017
openaire   +3 more sources

TlyA is a 23S and 16S 2′-O-methylcytidine methyltransferase important for ribosome assembly in Bacillus subtilis [PDF]

Jennie L Hibma, Lia M Munson, Joshua D. Jones, Taylor M. Nye, Kristin S. Koutmou, Lyle A. Simmons   +5 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Amplicon-based sequencing as a diagnostic tool for severe pneumonia in the ICU. [PDF]

Sci Rep
Michel C, Imamura H, Yin N, Etienne I, Nobile L, Chu M, Demuyser T, Bogaert D, Hites M, Vandenberg O, Hallin M.   +10 more
europepmc   +1 more source

Genomes and full-length 16S reference sequences for 27 Alpha- and Gamma-Proteobacterial isolates from Red Sea Acropora corals

, 2021
Anny Cárdenas, Christian R. Voolstra
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Circulating microbiome profiling in transjugular intrahepatic portosystemic shunt patients: 16S rRNA vs. shotgun sequencing. [PDF]

Front Med (Lausanne)
Zhang J, Xu X, Chen L, Yang X, Matsubara JK, Tian Y, Liu J, Jin X, Chang H, Xu M, Zhu C, Wang X, Ren L, Xie J, Liu J, Liu G, Lu M, Wang X, Du L, Ma Z, Liu X, Zhao H, Chen W, Huo X, Zheng G, Xie C, Xu C, Zhang X, Qi W, Feng Z.   +29 more
europepmc   +1 more source

Primer kok kanal enfeksiyonlarında Tannerella forsythia prevalansının 16S rRNA PCR ile incelenmesi

, 2010
ATASOY ULUSOY, Özgür Özgür, Güliz ENGİN, Doruk Doruk   +3 more
openalex   +1 more source