Results 291 to 300 of about 736,237 (386)

Abstracts (Part 16 of 16)

Transfusion Medicine and Hemotherapy, 1994
openaire   +1 more source

Application of SmartGene IDNS Software to Partial 16S rRNA Gene Sequences for a Diverse Group of Bacteria in a Clinical Laboratory

, 2006
Keith E. Simmon, Ann Croft, Cathy A. Petti   +2 more
openalex   +1 more source

ContEst16S: an algorithm that identifies contaminated prokaryotic genomes using 16S RNA gene sequences.

International Journal of Systematic and Evolutionary Microbiology, 2017
Imchang Lee, M. Chalita, Sung-min Ha, Seong-In Na, Seok-Hwan Yoon, J. Chun   +5 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Profiling of vaginal microbial communities in Chilean women via self-sampling and nanopore sequencing. [PDF]

Sci Rep
Oliva-Arancibia B, Villanueva P, Ugalde JA.   +2 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Refining microbiome resolution: KoSCAPE_bio identifies <i>Klebsiella oxytoca</i> complex species in16S rRNA amplicon data and uncovers associations with NEC. [PDF]

Gut Microbes
Cosic A, Halwachs B, Schild-Prüfert K, Zechner EL, Kienesberger S.   +4 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Assessing the Oral Microbiome in Women of Reproductive Age: A Narrative Review. [PDF]

Clin Pract
Ionaș TH, Ionaș M, Chicea R, Dădârlat DA, Ștef L.   +4 more
europepmc   +1 more source

Catheter-Related Microbacterium Bacteremia Identified by 16S rRNA Gene Sequencing

, 2002
Susanna K. P. Lau, Patrick C. Y. Woo, Gibson K. S. Woo, Kwok‐Yung Yuen   +3 more
openalex   +1 more source