Results 51 to 60 of about 736,237 (386)

Clinical Significance of a 16S-rDNA Analysis of Heart Valves in Patients with Infective Endocarditis: a Retrospective Study

open access: yesMicrobiology Spectrum, 2023
A substantial proportion of patients with infective endocarditis (IE) are subjected to heart valve surgery. Microbiological findings on valves are important both for diagnostics and for tailored antibiotic therapy, post-operatively.
Gustav Johansson   +3 more
doaj   +1 more source

One Health Spread of 16S Ribosomal RNA Methyltransferase-Harboring Gram-Negative Bacterial Genomes: An Overview of the Americas

open access: yesPathogens, 2023
Aminoglycoside antimicrobials remain valuable therapeutic options, but their effectiveness has been threatened by the production of bacterial 16S ribosomal RNA methyltransferases (16S-RMTases).
Fábio Parra Sellera   +2 more
doaj   +1 more source

Tertiary-Treated Municipal Wastewater is a Significant Point Source of Antibiotic Resistance Genes Into Duluth-Superior Harbor [PDF]

open access: yes, 2011
In this study, the impact of tertiary-treated municipal wastewater on the quantity of several antibiotic resistance determinants in Duluth-Superior Harbor was investigated by collecting surface water and sediment samples from 13 locations in Duluth ...
Allen H. K.   +49 more
core   +3 more sources

The effect of taxonomic classification by full-length 16S rRNA sequencing with a synthetic long-read technology

open access: yesScientific Reports, 2021
Characterizing the microbial communities inhabiting specimens is one of the primary objectives of microbiome studies. A short-read sequencing platform for reading partial regions of the 16S rRNA gene is most commonly used by reducing the cost burden of ...
Jinuk Jeong   +10 more
semanticscholar   +1 more source

Evaluating the Genetic Overlap Between Congenital Heart Disease and Neuroblastoma Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children with congenital heart disease (CHD) have elevated neuroblastoma (NB) risk, potentially due to shared neural crest origins. We analyzed rare exonic de novo single‐nucleotide variants in 702 CHD and 454 NB trios from the Neuroblastoma Epidemiology in North America Study, Gabriella Miller Kids First Program, and a published cohort. Seven
Ji Yun Tark   +7 more
wiley   +1 more source

Species identification based on the fecal DNA samples of the Caprinae

open access: yesActa Biologica Sibirica
Fecal analysis is a useful tool for studying the species identity of rare mammals. The possibility of using non-invasive biological materials in molecular genetic studies of rare bovids is shown, using the example of the markhor and Siberian ibex of ...
Abdurakhim E. Kuchboev   +5 more
doaj   +1 more source

Revised version (INFD-D-20-00242): impact of 16S rDNA sequencing on clinical treatment decisions: a single center retrospective study

open access: yesBMC Infectious Diseases, 2021
Background PCRs targeting 16S ribosomal DNA (16S PCR) followed by Sanger’s sequencing can identify bacteria from normally sterile sites and complement standard analyzes, but they are expensive.
Axel Ursenbach   +6 more
doaj   +1 more source

Targeting the 16S rRNA Gene by Reverse Complement PCR Next-Generation Sequencing: Specific and Sensitive Detection and Identification of Microbes Directly in Clinical Samples

open access: yesMicrobiology Spectrum, 2023
The detection and accurate identification of bacterial species in clinical samples are crucial for diagnosis and appropriate antibiotic treatment. To date, sequencing of the 16S rRNA gene has been widely used as a complementary molecular approach when ...
Simone J. C. F. M. Moorlag   +6 more
doaj   +1 more source

The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information [PDF]

open access: yes, 2010
The human oral microbiome is the most studied human microflora, but 53% of the species have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are known primarily from 16S rRNA sequence information.
Baranova, Oxana V.   +5 more
core   +1 more source

Differential Functional Constraints Cause Strain-Level Endemism in Polynucleobacter Populations. [PDF]

open access: yes, 2016
The adaptation of bacterial lineages to local environmental conditions creates the potential for broader genotypic diversity within a species, which can enable a species to dominate across ecological gradients because of niche flexibility.
Geeta Rijal   +8 more
core   +2 more sources

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