Results 151 to 160 of about 1,073,094 (328)

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

Advanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen, Haiyang Gao, Wang Wu, Pengzhi Shi, Yuhang Chen, Anran Zhang, Zhangrong Cheng, Wenbo Wu, Zimu Yu, Yukun Zhang   +9 more
wiley   +1 more source

EzTaxon: a web-based tool for the identification of prokaryotes based on 16S ribosomal RNA gene sequences.

International Journal of Systematic and Evolutionary Microbiology, 2007
J. Chun, Jae-Hak Lee, Yoonyoung Jung, Myungjin Kim, Seil Kim, Byung Kwon Kim, Y. Lim   +6 more
semanticscholar   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

The control of ribosomal RNA synthesis in mammalian cells

, 2013
The biogenesis of ribosomes is a fundamental process that occurs in all living cells. In mammalian cells, it is a highly complex process consisting of the coordinated synthesis and assembly of four ribosomal RNAs (rRNAs) with about 80 ribosomal proteins (
Zhang, Ze
core   +1 more source

30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. [PDF]

Proc Natl Acad Sci U S A, 2023
Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock LR, Dunham CM, Conn GL.   +6 more
europepmc   +1 more source

The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.

Proceedings of the National Academy of Sciences of the United States of America, 1974
John Shine, L. Dalgarno
semanticscholar   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

Advanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao, Ting‐Yu Han, Yan‐Li Cheng, Yi‐Dan Zhang, Yu‐Wei Zhang, JinJian Guo, ShaoJun Zhang, WenZe Huang, Jing Zhang, Pei‐Yu Liao, Ying Xin, ChuanChen Chu, Qing‐Yuan Sun, ZhiZhen Liu, Xiang‐Hong Ou, Jun Xie   +15 more
wiley   +1 more source

EFFECTIVENESS OF BACILLUS THURINGIENSIS AS A BIOCONTROL AGENT AGAINST ROOT-KNOT NEMATODES ON TOMATO PLANT

The Iraqi Journal of Agricultural science
This study aimed to evaluate the nematicidal effect of three local Bacillus thuringiensis isolates in controlling the root-knot nematodes Meloidogyne spp. under laboratory and shade house conditions.
Saad T. A. Yass, Khalid M. Al-Juhaishi, Sarah Tareq Hasan, Deepak K. Sinha   +3 more
doaj   +1 more source

CRISPR/Cas9-based depletion of 16S ribosomal RNA improves library complexity of single-cell RNA-sequencing in planarians. [PDF]

BMC Genomics, 2023
Wang KT, Adler CE.
europepmc   +1 more source

Complete nucleotide sequence of a 16S ribosomal RNA gene from Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America, 1978
Jürgen Brosius, M. L. Palmer, Poindexter J. Kennedy, H. Noller   +3 more
semanticscholar   +1 more source