Results 191 to 200 of about 1,073,094 (328)

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Detection of Pathogenic Bacteria From Septic Patients Using 16S Ribosomal RNA Gene-Targeted Metagenomic Sequencing. [PDF]

Clin Infect Dis, 2021
Fida M, Wolf MJ, Hamdi A, Vijayvargiya P, Esquer Garrigos Z, Khalil S, Greenwood-Quaintance KE, Thoendel MJ, Patel R.   +8 more
europepmc   +1 more source

Staphylococcus xylosus strain X18 16S ribosomal RNA gene, partial sequence

, 2007
Staphylococcus xylosus strain X18 16S ribosomal RNA gene, partial sequence GenBank: EF424595.
PRETTI, CARLO, SOLDANI, GIULIO, Jousson O, INTORRE, LUIGI, VANNI, MICHELE, Cardini G, DI BELLO, DOMENICA   +6 more
core  

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

Staphylococcus felis strain I77 16S ribosomal RNA gene, partial sequence

, 2007
Staphylococcus felis strain I77 16S ribosomal RNA gene, partial sequence GenBank: EF424584.
PRETTI, CARLO, SOLDANI, GIULIO, Jousson O, INTORRE, LUIGI, VANNI, MICHELE, Cardini G, DI BELLO, DOMENICA   +6 more
core  

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

Advanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko, Dongyoon Shin, Junho Park, June Huh, Youngsoo Kim, Jong‐Wan Park   +5 more
wiley   +1 more source

Clinical usefulness of 16S ribosomal RNA real-time PCR for the diagnosis of scrub typhus. [PDF]

Sci Rep, 2021
Yun NR, Kim CM, Kim DY, Seo JW, Kim DM.
europepmc   +1 more source

Staphylococcus haemolyticus strain X65 16S ribosomal RNA gene, partial sequence

, 2007
Staphylococcus haemolyticus strain X65 16S ribosomal RNA gene, partial sequence GenBank: EF424590.
PRETTI, CARLO, SOLDANI, GIULIO, Jousson O, INTORRE, LUIGI, VANNI, MICHELE, Cardini G, DI BELLO, DOMENICA   +6 more
core  

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

Design, Synthesis, and Evaluation of Novel Inhibitors of Aminoglycoside-Resistance 16S Ribosomal RNA Methyltransferases. [PDF]

ChemMedChem
Deprez BE, Dey D, Zelinskaya N, Csatary EE, Yang QW, Nie M, Conn GL, Wuest WM.   +7 more
europepmc   +1 more source