Results 281 to 290 of about 396,782 (350)

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

Skin Microbiome alterations in heroin users revealed by full-length 16S rRNA sequencing. [PDF]

open access: yesBMC Microbiol
Tao R   +7 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

open access: yesCancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang   +18 more
wiley   +1 more source

Comparative analysis of illumina and oxford nanopore sequencing platforms for 16S rRNA profiling of respiratory microbial communities. [PDF]

open access: yesSci Rep
Macip G   +12 more
europepmc   +1 more source

Amazonian Cyanobacteria as a Source of Bioactive Compounds With Antimicrobial and Cytotoxic Properties

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Cyanobacteria are photosynthetic microorganisms known for producing diverse bioactive compounds. This study explores the bioactivity of extracts and fractions from Amazonian cyanobacteria and their pigment and phenolic compound production. A fraction from Synechococcus sp. CACIAM 05 showed cytotoxicity against hCMEC/D3 and MG‐63 cells.
Samuel Cavalcante do Amaral   +8 more
wiley   +1 more source

A curated bacterial and archaeal 16S rRNA Gene Oral Sequences dataset. [PDF]

open access: yesSci Data
Vázquez-González L   +4 more
europepmc   +1 more source

Microbial mediation and climatic control on dolomite precipitation in a hypersaline lake: Insights from Salinas Lake, southern Iberia

open access: yesThe Depositional Record, EarlyView.
The cyclical nature of aridity and humidity led to the alternating deposition of dolomite‐rich and calcite‐rich sediments. During arid phases, the lake hydrology and growth of microbial mats under evaporative and hypersaline environment favors the precipitation of dolomite.
Guolai Li   +6 more
wiley   +1 more source

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