Results 231 to 240 of about 253,664 (304)

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki   +9 more
wiley   +1 more source

Intratumoral Fusobacterium nucleatum Drives Cancer‐Associated Fibroblasts Enrichment and Immune Exclusion in Esophageal Squamous Cell Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi   +9 more
wiley   +1 more source

Fimbriae‐Targeted Peptide‐Selenoviologen Cyclophane Complex for Enhanced Photodynamic Therapy of Periodontitis

open access: yesAggregate, EarlyView.
This study develops a supramolecular photosensitizer (SeVB⊃PQ) by combining SeVB with a P. gingivalis‐targeting peptide. SeVB⊃PQ selectively binds P. gingivalis, boosts ROS generation under irradiation, disrupts ATP synthesis, restores microbial balance, reduces inflammation, and promotes alveolar bone regeneration, offering a promising platform for ...
Rui Ding   +7 more
wiley   +1 more source

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing   +4 more
wiley   +1 more source

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