Results 231 to 240 of about 246,967 (290)

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Mechanism analysis of Tongqiao Yizhi decoction in treating vascular dementia rats by brain tissue untargeted metabonomics and fecal 16S rRNA gene sequencing. [PDF]

J Tradit Chin Med
Raoqiong W, Linyao H, Ye LU, Lingxue W, Jianrong LI, Yan P, Hongmei T, Shuangyang LI, Xue B.   +8 more
europepmc   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Exploring the Impact of Altitude on Bacterial Communities in Informally Produced Artisanal Colonial Cheeses: Insights from 16S rRNA Gene Sequencing. [PDF]

Microorganisms
Oliveira WC, de Freitas AS, Ströher JA, Richards NSPDS, Oliveira MBPP, Erhardt MM.   +5 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Evaluating the Effect of Dietary Protein-Energy Ratios on Yak Intestinal Microbiota Using High-Throughput 16S rRNA Gene Sequencing. [PDF]

Vet Sci
Zhu Y, Cidan Y, Ali M, Lu S, Javed U, Cisang Z, Gusang D, Danzeng Q, Li K, Basang W.   +9 more
europepmc   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Combined analysis of 16S rRNA gene sequencing data reveals core vaginal bacteria across livestock species. [PDF]

Front Microbiol
Jonas LC, Youngs CR, Schmitz-Esser S.
europepmc   +1 more source

Phylogenomics and Biogeography of the Eastern Asian–Eastern North American Disjunct Genus Hylodesmum (Fabaceae)

Biological Diversity, EarlyView.
Integrating data from plastid genomes, nrDNA, and 353 low‐copy nuclear genes, this study establishes a robust phylogenetic framework for Hylodesmum. This framework supports a taxonomic revision recognizing 18 species and reveals a complex pattern of bidirectional EA–ENA dispersal, with mammals as a plausible dispersal agent. ABSTRACT Phylogenomics with
Zhuqiu Song, Gang Yao, Chen Ren, Kaiwen Jiang, Dongxian Xu, Shijin Li   +5 more
wiley   +1 more source

Standardization of 16S rRNA gene sequencing using nanopore long read sequencing technology for clinical diagnosis of culture negative infections. [PDF]

Front Cell Infect Microbiol
Butler I, Turner O, Mohammed K, Akhtar M, Evans D, Lambourne J, Harris K, O'Sullivan DM, Sergaki C.   +8 more
europepmc   +1 more source