Results 131 to 140 of about 107,985,804 (238)

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Waffen-SS : Eintritt nach vollendetem 17. Lebensjahr

, 1940
O Anton. Hrsg. vom SS-Hauptamt, Ergänzungsamt der Waffen-SS, BerlinKünstlersign.

core   +1 more source

Steady-State Pharmacokinetic Drug-Drug Interaction Study of Zastaprazan, a Novel Potassium-Competitive Acid Blocker, and Atorvastatin in Healthy Participants. [PDF]

Drug Des Devel Ther
Yang AY, Kim H, Yoo H, Lee YS, Kim J, Shin W.   +5 more
europepmc   +1 more source

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source

Activation of Platelet Caspase-1 and P-Selectin Over-Expression in Sickle Cell Disease Patients: An Involvement of NLRP3 Inflammasome? [PDF]

J Cell Mol Med
Claude L, Martino F, Mordier L, Célanie D, Bernit E, Etienne-Julan M, Tressières B, Romana M, Baccini V.   +8 more
europepmc   +1 more source

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

Advanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo, Seon Min Woo, Minhyeong Choi, Soeun Rhee, Simmyung Yook, Donghyuk Shin, Kwang‐Su Park, Taeg Kyu Kwon   +7 more
wiley   +1 more source

SS VICTORIAN at sea, Washington State, between 1892 and 1902

, 1892
The SS VICTORIAN was an American passenger steamship out of Portland, OR and later Tacoma, WA. She was built by J.H. Steffen, Portland Oregon. She was sold to Canadian owners and converted into a car ferry in 1903.
Hester, Wilhelm, 1870-1947
core  

Electrochemical corrosion properties of a novel sodium hyaluronate and zinc oxide nanoparticle-coated stainless steel orthodontic arch wire - an in-vitro study. [PDF]

Biomater Investig Dent
Pallikkara NV, Nagesh S, Sivashanmugam P, Sundari S.   +3 more
europepmc   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Cubic RSM modeling and multi-criteria evaluation of stainless-steel electrodes for EC of real carwash wastewater. [PDF]

Sci Rep
Madih K, Sayed NM, Ali RH, Mahmoud MS, Gamal H, Osama R.   +5 more
europepmc   +1 more source