Results 121 to 130 of about 23,700,718 (245)

Integrated untargeted metabolomics and lipidomics reveals functional- and taste-related compounds in stir-fried <i>Trichosanthis Semen</i>. [PDF]

Front Nutr
Wang Y, Wu D, Zhang X, Jia X, Ha L.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Blanche et Marie : 2 polkas-mazurkas pour le piano. N° 2 / par Henry Barbara ; [ill. par] Bertrand

Titre uniforme : Barbara, Henry (18..-18.. ; compositeur). Compositeur. [Blanche et Marie. Piano]Polkas-mazurkas (piano) -- +* 1800......- 1899......+:19e siècle:Piano, Musique de -- +* 1800......- 1899......+:19e ...
Barbara, Henry (18..-18.. ; compositeur). Compositeur
core  

Urolithin A activates aryl hydrocarbon receptor-NLRP6-mediated pathways in intestinal epithelial cells to modulate mucosal immunity and strengthen gut barrier integrity. [PDF]

Nat Commun
Ghosh S, Vanwinkle ZM, Bodduluri SR, Juin SK, Kadari M, Singh A, Dryden GW, Lawrenz MB, Kanneganti TD, Rai SN, Good M, Kumar P, Haribabu B, Jala VR.   +13 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Souvenir de Rouen : polka-mazurka / par Chéron ; [ill. par] Bertrand

Titre uniforme : Chéron, L. (18..-18..? ; compositeur). Compositeur. [Souvenir de Rouen. Piano]Appartient à l’ensemble documentaire : HNormand1Polkas-mazurkas (piano) -- +* 1800......- 1899......+:19e siècle:Piano, Musique de -- +* 1800......- 1899......
Chéron, L. (18..-18..? ; compositeur). Compositeur
core  

A Coupled Inflammatory-Fibrotic-Nitrosative Axis in Patients with Patent Foramen Ovale and Cryptogenic Stroke. [PDF]

J Clin Med
Tworek M, Trojanowicz K, Sachajko Z, Kowalik-Pandyra M, Pacia K, Bielecka K, Szczepara S, Tworek M, Natorska J, Kopeć G, Komar M.   +10 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Le mirliton du diable : quadrille brillant pour le piano : [op. 253] / par Blancheteau ; [ill. par] Caille

Titre uniforme : Blancheteau, A. (18..-18.. ; compositeur). Compositeur. [Le mirliton du diable. Piano. Op. 253]Quadrilles (piano) -- +* 1800......- 1899......+:19e siècle:Piano, Musique de -- +* 1800......- 1899......+:19e ...
Blancheteau, A. (18..-18.. ; compositeur). Compositeur
core  

PLAT 18(3) 2019 [PDF]

Psychology Learning & Teaching, 2019
openaire   +1 more source