Results 21 to 30 of about 126,237 (251)

Sex hormones play a role in vulnerability to sleep loss on emotion processing tasks

open access: yesNeurobiology of Sleep and Circadian Rhythms, 2018
The central aim of this study was to investigate hormones as a predictor of individual vulnerability or resiliency on emotion processing tasks following one night of sleep restriction. The restriction group was instructed to sleep 3 a.m.–7 a.m.
K.A. Lustig   +5 more
doaj   +1 more source

Hyperarousal Is Associated with Socioemotional Processing in Individuals with Insomnia Symptoms and Good Sleepers

open access: yesBrain Sciences, 2020
Despite complaints of difficulties in waking socioemotional functioning by individuals with insomnia, only a few studies have investigated emotion processing performance in this group.
Reuben D. M. Howlett   +3 more
doaj   +1 more source

Crystal structure and solvent-dependent behaviours of 3-amino-1,6-diethyl-2,5,7-trimethyl-4,4-diphenyl-3a,4a-diaza-4-bora-s-indacene

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
In the title compound (3-amino-4,4-diphenyl-BODIPY), C28H32BN3, the central six-membered ring has a flattened sofa conformation, with one of the N atoms deviating by 0.142 (4) Å from the mean plane of the other five atoms, which have an r.m.s.
Lijing Yang   +6 more
doaj   +1 more source

On the separation of the Moldavian estates after the Bucharest Peace (1812). Several additions [PDF]

open access: yesDiacronia, 2019
After the occupation of Moldavia between the Pruth and the Dniester, the Russian Empire imposed, through the Bucharest peace, to the estate owners to choose within 18 months the country side where they would live. For a while, the Romanians believed that
Petronel Zahariuc
doaj   +1 more source

The relationship between concussion and alcohol consumption among university athletes

open access: yesAddictive Behaviors Reports, 2018
Introduction: This study investigated concussion as a potential risk factor for increased alcohol consumption in university athletes. Methods: Using a cross-sectional design, 41 university students (37% with a history of concussion) completed self-report
Bradey Alcock   +2 more
doaj   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

open access: yesAdvanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang   +7 more
wiley   +1 more source

A Low-Therapeutic Dose of Lithium Inhibits GSK3 and Enhances Myoblast Fusion in C2C12 Cells

open access: yesCells, 2019
Glycogen synthase kinase 3 (GSK3) slows myogenic differentiation and myoblast fusion partly by inhibiting the Wnt/β-catenin signaling pathway. Lithium, a common medication for bipolar disorder, inhibits GSK3 via Mg+ competition and increased Ser21 ...
Nigel Kurgan   +11 more
doaj   +1 more source

Grandparent Prenatal Tobacco, Alcohol, Coffee, and Tea Consumption and Autism in the Third Generation

open access: yesAutism Research, EarlyView.
ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl   +6 more
wiley   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara   +20 more
wiley   +1 more source

Association of BMI with adherence and outcome in heart failure patients treated with wearable cardioverter defibrillator

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1295-1303, April 2025.
Abstract Background Obesity is a known risk factor for cardiovascular disease (CVD), yet an ‘obesity paradox’ has been observed in various CVD contexts. The impact of obesity on heart failure (HF) patients treated with a wearable cardioverter‐defibrillator (WCD) remains underexplored.
Mohammad Abumayyaleh   +18 more
wiley   +1 more source

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