[18F]mFBG PET/CT surpasses [18F]FDG PET/CT for evaluation of pediatric neuroblastoma [PDF]
Frontiers in OncologyPurpose[18F]FDG PET/CT serves as an alternative imaging modality for neuroblastoma in cases where [123I]MIBG yields negative results or is unavailable. [18F]mFBG, a novel PET tracer for neuroblastoma imaging, requires further clinical validation.
Wenqian Zhang +11 more
doaj +2 more sources
18F-Fluorination of 2-methyl-6-nitrobenzenesulfonate ester and its application to the synthesis of a 18F-labeled amino acid. [PDF]
, 2023 In the development of an efficient 18F-labeling method for the synthesis of PET tracers, it is essential not only to improve the efficiency of [18F]fluorine incorporation into a carrier but also to minimize non-radioactive side products from the ...
Jun, Toyohara +4 more
core +1 more source
Scalable 18F Processing Conditions for Copper-Mediated Radiofluorination Chemistry Facilitate "Design of Experiments" (DoE) Optimization Studies and Afford an Improved Synthesis of [18F]Olaparib. [PDF]
, 2021 A convenient, scalable, and azeotropic drying free method for processing [18F]fluoride as base free[18F]TBAF is reported and applied to copper-mediated radiofluorination (CMRF) radiosyntheses.
Gregory D., Bowden +3 more
core +2 more sources
, 2022 Objective: To evaluate the maximum and mean standardized uptake values, together with the metabolic tumor value and the total lesion glycolysis, at the primary tumor site, as determined by 18F-fluorodeoxyglucose positron-emission tomography/computed ...
Paulo Schiavom Duarte (12702843) +7 more
core +2 more sources
Construction and Evaluation of Quantitative Small-Animal PET Probabilistic Atlases for [18F]FDG and [18F]FECT Functional Mapping of the Mouse Brain [PDF]
, 2013 Automated voxel-based or pre-defined volume-of-interest (VOI) analysis of small-animal PET data in mice is necessary for optimal information usage as the number of available resolution elements is limited. We have mapped metabolic ([18F]FDG) and dopamine
Kathleen Vunckx (419666) +27 more
core +1 more source
, 2022 Increased glutamine metabolism by macrophages is associated with development of atherosclerotic lesions. Positron emission tomography/computed tomography (PET/CT) with a glutamine analog (2S,4R)-4-18F-fluoroglutamine (18F-FGln) allows quantification of ...
Aarthi Ravindran (11995724) +11 more
core +1 more source
Development of Novel Fluorine-18 Labeled PET Radioligands for Monoamine Oxidase B (MAO-B) [PDF]
, 2013 Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and ...
Nag, Sangram
core +1 more source
World Journal of Nuclear Medicine, 2020 We report the efficacy of dual positron emission tomography/computed tomography (PET/CT) imaging with [18F]-2'-fluoro-2'-deoxy-D-glucose ([18F]-FDG) and [18F]-fluorocholine ([18F]-FCH) in patients with gestational trophoblastic neoplasia (GTN) for ...
Tanyaluck Thientunyakit +3 more
doaj +1 more source
Kinetic Modeling and Graphical Analysis of 18F-Fluoromethylcholine (FCho), 18F-Fluoroethyltyrosine (FET) and 18F-Fluorodeoxyglucose (FDG) PET for the Fiscrimination between High-Grade Glioma and Radiation Necrosis in Rats. [PDF]
PLoS ONE, 2016 BACKGROUND:Discrimination between glioblastoma (GB) and radiation necrosis (RN) post-irradiation remains challenging but has a large impact on further treatment and prognosis.
Julie Bolcaen +10 more
doaj +1 more source
Automatic Production and Preliminary PET Imaging of a New Imaging Agent [18F]AlF-FAPT
Frontiers in Oncology, 2022 BackgroundFibroblast activating protein (FAP) has become an important target for cancer diagnostic imaging and targeted radiotherapy. In particular, [18F]FAPI-42 has been successfully applied to positron emission tomography (PET) imaging of various ...
JiaWen Huang +8 more
doaj +1 more source