Results 291 to 300 of about 134,822 (364)

PMAT2: An efficient graphical assembly toolkit for comprehensive organellar genomes

open access: yesiMeta, EarlyView.
We developed PMAT2, an advanced toolkit for lineage‐specific de novo assembly of plant, animal, and fungal mitochondrial genomes, as well as plant chloroplast genome. PMAT2 leverages optimized graph‐based strategies tailored to organelle genome complexity, enabling complete and accurate assemblies, even with approximately 1 × highly accurate PacBio ...
Fuchuan Han   +10 more
wiley   +1 more source

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang   +4 more
wiley   +1 more source

Reference genes validation in tear fluid for RNA analysis in ocular surface disease. [PDF]

open access: yesSci Rep
Ojeda DA   +7 more
europepmc   +1 more source

Telomere‐Related Gene Networks in the Ovary Shift Across Environmental Factors

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ovary is key to linking environmental factors with the timing and quality of offspring development. Focused on free‐living female tree swallows (Tachycineta bicolor), we measured temporal variation in ovarian expression of genes involved in the regulation of telomere length.
Sarah E. Wolf   +3 more
wiley   +1 more source

Calcium butyrate efficacy in pediatric irritable bowel syndrome: Randomized placebo‐controlled multiomics‐based clinical trial

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, and treatment involves nonpharmacological and pharmacological therapies, even if there is no optimal therapy. This randomized, placebo‐controlled, double‐blind trial aimed to evaluate the efficacy of calcium butyrate supplementation in ...
Fernanda Cristofori   +11 more
wiley   +1 more source

Nuisance alga reduces lake partial pressure of carbon dioxide and carbon flux to the atmosphere in boreal lakes

open access: yesLimnology and Oceanography, EarlyView.
Abstract Boreal lakes are generally seen as sources of carbon dioxide (CO2) to the atmosphere, even though a part of them are periodically undersaturated with CO2 and have the potential to be net‐autotrophic. This undersaturation is the result of photosynthetic activity by phytoplankton, especially flagellated species like Gonyostomum semen, which form
Karla Münzner   +2 more
wiley   +1 more source

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