Results 91 to 100 of about 12,169,803 (276)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Polcos (illustrateur non-identifié 19..?-19..?) : signature [1926]

, 1926
Polcos (illustrateur non-identifié 19..?-19..?) : signature [1926] ; aucune information biographique sur l’artiste signant “Polcos”
Polcos (illustrateur N.I. 19..-19..), ., Daphy, Éliane   +1 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tob Würth (illustrateur 19..-19..? ) : signature “Würth”

, 1937
Tob Würth (illustrateur 19..-19..?
Tob Würth (illustrateur 19..-19..), ., Daphy, Éliane   +1 more
core  

COVID-19

Revista Brasileira de Medicina do Trabalho, 2022
Henry, Timothy D., Garcia, Santiago
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Editorial 19/2 and 19/3 [PDF]

Electronic Markets, 2009
Hubert Österle, Karen Heyden
openaire   +1 more source

Temporal characteristics of the fore-aftershock sequences of the 1999 Mw7.5 Turkey earthquake [PDF]

GeoStudies
Strong earthquake with moment magnitude MW7.5 hit the city of İzmit, Turkey with devastating effect in August 1999. The earthquake occurred in the North Anatolian Fault (NAF),and was followed by an intensive aftershock activity.
Plamena Raykova, Dimcho Solakov, Stela Simeonova   +2 more
doaj   +3 more sources