Results 161 to 170 of about 3,869,530 (293)

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

open access: yesChemistry – A European Journal, EarlyView.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito   +3 more
wiley   +1 more source

Structural Aspects of Lithium‐Ion Conduction in the Phosphidotitanate Li8TiP4 and Its Comparison With Li7+5xTa1−xP4 and Li8−xTi1−xTaxP4

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT The chemical system Li/Ti/P has previously been subject to intensive investigation. However, reliable structural data for the reported phases have remained elusive. Motivated by the growing interest in phosphorus‐based lithium‐ion conductors, we have reinvestigated the synthesis, crystal structure, and physical properties of Li8TiP4.
David Müller   +6 more
wiley   +1 more source

T‐calibration in semi‐parametric models

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract This article relates the calibration of models to the consistent loss functions for the target functional of the model. Correctly specified models are calibrated. Conversely, we demonstrate that if there is a parameter value that is optimal under all consistent loss functions, then a model is calibrated.
Anja Mühlemann, Johanna Ziegel
wiley   +1 more source

C‐Terminal Tail Elongation Adds a New Dimension to the Tubulin Code

open access: yesCytoskeleton, EarlyView.
ABSTRACT Tubulin C‐terminal tails undergo diverse post‐translational modifications that regulate microtubule interactions with motors and severing enzymes. TTLL11, a member of the tubulin tyrosine ligase‐like (TTLL) family, uniquely catalyzes glutamate addition to the terminal α‐carboxyl group of both α‐ and β‐primary tubulin tails.
Jana Campbell, Cyril Barinka
wiley   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

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