Results 171 to 180 of about 1,079,697 (312)

Cobalt/Photoredox Catalyzed Desymmetrization of Oxo and Azabicycles via Asymmetric Reductive Coupling With Alkynes

open access: yesAdvanced Science, EarlyView.
A one‐step, asymmetric reductive coupling of alkynes and oxa‐ and aza‐bicyclic olefins using a cobalt/photoredox catalytic system through desymmetrization. ABSTRACT Bicyclo[2.2.1]heptane frameworks represent a privileged structural motif prevalent in numerous natural products and bioactive molecules.
Subhankar Pradhan   +5 more
wiley   +1 more source

A longitudinal <sup>1</sup>H NMR-based urinary metabolomics dataset in a birth cohort for childhood atopic diseases. [PDF]

open access: yesSci Data
Kuo YH   +9 more
europepmc   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

Quantitative liquid-state <sup>1</sup>H NMR as a tool to map phase diagrams of oleogels. [PDF]

open access: yesCurr Res Food Sci
Yilmazer S   +7 more
europepmc   +1 more source

A Triple‐Nanoparticle System for Controlled Graphene Nanosheet Stacking: Enabling K/Na‐Ion Battery Anodes with Ultra‐Fast Charging Exceeding Petroleum Vehicle Refueling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Large‐ion (K, Na) battery systems mitigate uneven global lithium distribution, while their ability to attain recharge time shorter than refueling would remove the final barrier for secondary batteries to replace petroleum vehicles. However, their large‐ion chemistry makes ultra‐fast charging an even significant challenge.
Shukai Ding   +12 more
wiley   +1 more source

Leveraging metabolic similarity in a <sup>1</sup>H NMR database of medicinal plants to advance pharmacognostic insights. [PDF]

open access: yesSci Rep
Seo S   +10 more
europepmc   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

1H-NMR-based metabolomics identifies disrupted betaine metabolism as distinct serum signature of pre-frailty. [PDF]

open access: yesNPJ Aging
Marino C   +14 more
europepmc   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

open access: yesAdvanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin   +12 more
wiley   +1 more source

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