Results 11 to 20 of about 18,047,458 (165)

Osteoarthritis and risk of type 2 diabetes: A two‐sample Mendelian randomization analysis 骨关节炎与2型糖尿病的风险:一项双样本孟德尔随机化分析 [PDF]

Journal of Diabetes, Volume 15, Issue 11, Page 987-993, November 2023., 2023
Highlights We used data from the genome‐wide association studies database and two‐sample mendelian randomization method, we found that genetic evidence supporting that knee osteoarthritis is a potential risk factor for type 2 diabetes. Abstract Background Physical inactivity is an independent risk factor for type 2 diabetes (T2D).
Xing Xing, Yining Wang, Faming Pan, Guoqi Cai   +3 more
wiley   +2 more sources

谷氨酸脱羧酶抗体对 1 型糖尿病的诊断意义 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 1998
目的: 探讨谷氨酸脱羧酶(GAD)抗体与 1 型糖尿病患者发病年龄、病程及临床特征等的关系。方法: 用放射免 疫沉淀法测定 92 例 1 型糖尿病和 53 例 2 型糖尿病患者血中 GAD 抗体。结果: 1 型糖尿病组总的 GAD 抗体阳性率为 39. 1%, 其中儿童 1 型糖尿病组、成人 1 型糖尿病组和成人晚发 1 型糖尿病组的阳性率分别为 46. 7%、36. 8%和 40. 0%,组间 无差异; 而病程≤1 a 的阳性率 58. 8%,明显高于病程>1 a 组的 27.
修玲玲　余斌杰　胡少眉　许善真　程　桦　曾龙驿
doaj   +1 more source

2型糖尿病视网膜病变与下肢血管病变的关系 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2017
【目的】探讨2型糖尿病患者糖尿病视网膜病变与下肢血管病变是否存在共同的危险因素及预测关系。【方法】 对99例糖尿病下肢血管病变的患者行双侧胫前动脉、胫后动脉、足背动脉共6条血管的超声检查，每条血管根据狭窄程度 评分，狭窄程度在30% ~ 49%评0分，50% ~ 99％评1分，管腔闭塞者（即狭窄100％）评2分，各段血管评分相加为总得分；0- 2分为1级，3 ~ 4分为2级，5 ~ 12分为3级。同时对这些患者行眼底检查，判断视网膜病变情况。分析2型糖尿病视网膜病 变与下肢血管病变的关系。【结果】
张丹乔, 戚以勤, 冯琬婷, 劳国娟   +3 more
doaj   +1 more source

2 型糖尿病患者合并肾脏疾病的临床病理及预后 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2020
【目的】探讨 2 型糖尿病（T2DM）患者合并肾脏疾病的临床病理特点及预后。【方法】回顾性分析120 例尿检异常和（或）Scr 升高并接受肾活检的2 型糖尿病患者的临床病理资料，并进行了随访。肾脏结局的定义是接受肾脏替代治疗或进入到终末期肾病（ESRD）。Kaplan-Meier 分析用于比较肾存活率，Cox 比例风险分析用于进行糖尿病肾病（DN）和非糖尿病肾脏疾病（NDRD）进入 ESRD 的风险比较。【结果】120 例 2 型糖尿病患者中，肾穿刺确诊DN57 例，占47.5%；NDRD63 例 ...
李明, 李灿明, 叶增纯, 饶嘉玲, 彭晖, 娄探奇   +5 more
doaj   +1 more source

Combined detection of urinary biomarkers noninvasively predicts extent of renal injury in patients with early diabetic kidney disease with kidney qi deficiency syndrome: A retrospective investigation

The Anatomical Record, Volume 306, Issue 12, Page 2945-2957, December 2023., 2023
Abstract Incipient diagnosis and noninvasive forecasts using urinary biomarkers are important for preventing diabetic kidney disease (DKD) progression, but they are also controversial. Previous studies have shown a potential relationship between urinary tubular biomarkers (UTBs) and traditional Chinese medicine (TCM) syndrome in patients with DKD. Thus,
Wei Wu, Xian‐Jie Meng, Bing‐Ying Wan, Qi‐Jun Fang, Ying‐Lu Liu, Jie Wang, Yan Fu, Can‐Can Yuan, Mei‐Zi Wang, Fee‐Lan Chong, Yi‐Gang Wan, Shan‐Mei Shen   +11 more
wiley   +1 more source

Rationale and design for the Blood Pressure Control Target in Diabetes (BPROAD) study 糖尿病血压控制目标(BPROAD)研究的原理和设计

Journal of Diabetes, Volume 15, Issue 12, Page 1029-1040, December 2023., 2023
Highlights The Blood Pressure Control Target in Diabetes (BPROAD) study is a multicenter, randomized controlled trial conducted in mainland China to test the hypothesis of whether intensive blood pressure (BP) management (systolic BP <120 mm Hg) has additional benefits over standard BP management (systolic BP <140 mm Hg) over a follow‐up period of up ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
wiley   +1 more source

Blood pressure targets for prevention of cognitive decline in patients with diabetes and hypertension: Design of the Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study 高血压目标对于预防糖尿病和高血压患者的认知下降:BPROAD认知研究的设计

Journal of Diabetes, Volume 15, Issue 12, Page 1041-1047, December 2023., 2023
Highlights The optimal blood pressure (BP) target in patients with type 2 diabetes mellitus (T2DM) for the management of cognitive decline remains unknown. The Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study was designed to determine whether intensive BP treatment (systolic BP <120 mm Hg) reduces risk of dementia and mild cognitive ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
wiley   +1 more source

Patient experiences of continuous glucose monitoring and sensor‐augmented insulin pump therapy for diabetes: A systematic review of qualitative studies 糖尿病患者接受连续血糖监测和传感器增强胰岛素泵治疗的体验:对定性研究的系统综述

Journal of Diabetes, Volume 15, Issue 12, Page 1048-1069, December 2023., 2023
Highlights We identified that CGM can increase motivation for self‐management and confidence in treatments. A supportive treating team may help to reduce the practical and psychological burden in patients with type 1 and type 2 diabetes. Abstract Aims Blood glucose control is central to the management of diabetes, and continuous glucose monitoring (CGM)
Patrizia Natale, Sharon Chen, Clara K. Chow, Ngai Wah Cheung, David Martinez‐Martin, Corinne Caillaud, Nicole Scholes‐Robertson, Ayano Kelly, Jonathan C. Craig, Giovanni Strippoli, Allison Jaure   +10 more
wiley   +1 more source

Early weight gain after diagnosis may have an impact on remission status in children with new‐onset type 1 diabetes mellitus 儿童新发1型糖尿病诊断后早期体重增加可能对缓解状态产生影响

Journal of Diabetes, Volume 15, Issue 12, Page 1011-1019, December 2023., 2023
Highlights Weight gain with insulin therapy in the early period may be negatively related to the occurrence and duration of remission by altering insulin sensitivity. Interventions to prevent rapid weight gain and conserve insulin sensitivity in the early stages of type 1 diabetes mellitus may be beneficial for the development and maintenance of ...
Dicle Canoruc Emet, Hande Nur Karavar, Onur Gozmen, Arife Aslan Agyar, Yağmur Ünsal, Merve Canturk, Pınar Cengiz, Dogus Vuralli, Z. Alev Ozon, E. Nazlı Gonc   +9 more
wiley   +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source