Results 51 to 60 of about 31,668 (274)

Molecular Dynamics Simulations of HEMA-Based Hydrogels for Ophthalmological Applications

Molecules
The structural and dynamic properties of poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(N-vinylpyrrolidone-co-2-hydroxyethyl methacrylate) [P(VP-co-HEMA)], dry and as hydrogels, were studied by molecular dynamics simulations. The P(VP-co-HEMA) chains
Katarzyna Filipecka-Szymczyk, Malgorzata Makowska-Janusik, Wojciech Marczak   +2 more
doaj   +1 more source

Evaluation of peritoneal adhesions formation and tissue response to polypropylene - poli (2-hydroxyethyl methacrylate)-(polyHEMA) implant on rats' abdominal wall Avaliação da formação de aderências peritoneais e da resposta tecidual ao implante de poli (2-hidroxietil dimetacrilato)-(poliHEMA) na parede abdominal de ratos

Acta Cirúrgica Brasileira, 2010
PURPOSE: To verify if the composit poli (2-hydroxyethyl methacrylate)-PolyHEMA/polypropylene mesh implanted in the female rat's abdominal wall could be suitable for the prevention of peritoneal adhesions, and for the evaluation of the tecidual response ...
Neusa Margarida Paulo, Sonia Maria Malmonge, Liliana Borges de Menezes, Flávia Gontijo de Lima, Aline de Moraes Faria, Mariana Moreira Andrasckho, Natalia Menezes Moreira, Ingrid Bueno Atayde, Marcelo Seixo de Brito e Silva   +8 more
doaj   +1 more source

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

Advanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal, Kai‐Po Fan, Sheng‐Chun Hung, Jaba Roy Chowdhury, Jun‐Hsun Chung, Meenakshi Ray, Hsiang‐Yun Hsu, Fu‐Cheng Kao, Kuei‐Lin Liu, Zong‐Hong Lin   +9 more
wiley   +1 more source

The effect of heterobifunctional crosslinkers on HEMA hydrogel modulus and toughness.

PLoS ONE, 2019
The use of hydrogels in load bearing applications is often limited by insufficient toughness. 2-Hydroxyethyl methacrylate (HEMA) based hydrogels are appealing for translational work, as they are affordable and the use of HEMA is FDA approved. Furthermore,
Elizabeth M Boazak, Vaughn K Greene, Debra T Auguste   +2 more
doaj   +1 more source

Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate

Journal of Materials Science: Materials in Medicine, 2002
This study compares subcutaneous and intracerebral biocompatibilty of two hydrogels: copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate and poly(2-hydroxyethyl methacrylate) as reference polymer. The experimental copolymer was more biologically inert than poly(2-hydroxyethyl methacrylate) in both the studied parameters ...
Martin, Prádný, Pavel, Petrovický, Václava, Fronková, Jirí, Vacík, Karel, Smetana   +4 more
openaire   +2 more sources

Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance

Advanced Intelligent Discovery, EarlyView.
Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen, Tianlong Liu, Chao Lu, Rimsha Malik, Jin Zhang   +4 more
wiley   +1 more source

The synthesis and degradation of collagenase-degradable poly(2-hydroxyethyl methacrylate)-based hydrogels and sponges for potential applications as scaffolds in tissue engineering

, 2012
A collagenase-cleavable peptide-based crosslinking agent was synthesized and was incorporated into PHEMA sponges, and P[HEMA-co-MeO-PEGMA] gels and sponges [HEMA 2-hydroxyethyl methacrylate, PHEMA = poly(2-hydroxyethyl methacrylate), MeO-PEGMA = poly ...
Paterson, S., Shadforth, Audra, Chirila, Traian, Baker, Murray, Madden, P., Baker, M., Brown, David, Shadforth, A., Chirila, Traian V., Chirila, T., Paterson, Stefan M., Brown, David H., Paterson, Stefan, Madden, Peter, Madden, Peter W., Shadforth, Audra M. A., Baker, Murray V.   +16 more
core   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

Advanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Real time in vitro studies of doxorubicin release from PHEMA nanoparticles

Journal of Nanobiotechnology, 2009
Background Many anticancer agents have poor water solubility and therefore the development of novel delivery systems for such molecules has received significant attention.
Bajpai AK, Chouhan Raje
doaj   +1 more source