Results 121 to 130 of about 161,336 (310)
DNCCLA: Discrete New Caledonian Crow Learning Algorithm for Solving Traveling Salesman Problem
Applied Computational Intelligence and Soft ComputingThe development of metaheuristic algorithms has led to the solution of various optimization problems. Bioinspired optimization algorithms like the New Caledonian crow learning algorithm (NCCLA) are primarily designed to address continuous problems.
Ali H. Alsaidi +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A Fast FPGA-Based 2-Opt Solver for Small-Scale Euclidean Traveling Salesman Problem
15th Annual IEEE Symposium on Field-Programmable Custom Computing Machines (FCCM 2007), 2007 Παρουσιάστηκε στο: 15th Annual IEEE Symposium on Field-Programmable Custom Computing ...
Παπαευσταθιου Ιωαννης(http://users.isc.tuc.gr/~ipapaefstathiou) +4 more
openaire +2 more sources
The 0-1 inverse maximum stable set problem [PDF]
Given an instance of a weighted combinatorial optimization problem and its feasible solution, the usual inverse problem is to modify as little as possible (with respect to a fixed norm) the given weight system to make the giiven feasible solution optimal.
Marc Demange, Yerim Chung
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Opt-Out Consent at Different Levels of Attitude to Organ Donation: A Household Survey in Qatar
Journal of Multidisciplinary Healthcare, 2021 Rajvir Singh,1 Betsy Varughese,2 Ayman El-Menyar,3 Saad Shahbal,1 Yousuf Al Maslamani,4 Amar M Salam,5 Hassan Al Thani3 1Cardiology Research Center, Heart Hospital, Hamad Medical Corporation (HMC), Doha, Qatar; 2Gastroenterology & Hepatology, HMC ...
Singh R +6 more
doaj
Tabu Search for the Single Row Facility Layout Problem Using Exhaustive 2-Opt and Insertion Neighborhoods [PDF]
The single row facility layout problem (SRFLP) is the problem of arranging facilities with given lengths on a line, while minimizing the weighted sum of the distances between all pairs of facilities. The problem is NP-hard.
Ghosh, Diptesh, Kothari, Ravi
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source