Results 151 to 160 of about 161,336 (310)

Effects of improved amino acid balance diet on lysine mammary utilization, whole body protein turnover and muscle protein breakdown on lactating sows

Journal of Animal Science and Biotechnology
Background The study objective was to test the hypothesis that low crude protein (CP) diet with crystalline amino acids (CAA) supplementation improves Lys utilization efficiency for milk production and reduces protein turnover and muscle protein ...
Sai Zhang, Juan C. Marini, Vengai Mavangira, Andrew Claude, Julie Moore, Mahmoud A. Mohammad, Nathalie L. Trottier   +6 more
doaj   +1 more source

Faculty Opinions recommendation of Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses.

, 2009
Achsah Keegan
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Additional file 2 of GATA2 co-opts TGFβ1/SMAD4 oncogenic signaling and inherited variants at 6q22 to modulate prostate cancer progression

, 2023
Xiayun Yang, Qin Zhang, Shuxuan Li, Raman Devarajan, Binjie Luo, Zenglai Tan, Zixian Wang, Nikolaos Giannareas, Tomasz Wenta, Wenlong Ma, Yuqing Li, Yuehong Yang, Aki Manninen, Song Wu, Gong‐Hong Wei   +14 more
openalex   +1 more source

2 Men Opting out: Disenchantment with Corporate Cultures and Career Ideals [PDF]

, 2020
Ingrid Biese
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Swallowing behavior response to semi-solid foods with different textural properties in healthy older adults: an open-label randomized crossover trial

JAR Life
Background: Semi-solid foods are widely consumed by older adults, yet the influence of their physical properties on swallowing remains unclear. Objectives: To examine how variations in shape retention and spreadability affect swallowing in adults aged ...
Masashi Tsujimoto, Tomoko Hisajima, Saho Matsuda, Keisuke Suzuki, Tomoya Shimokakimoto, Yoshio Toyama   +5 more
doaj   +1 more source

Corrigendum: Absolute single photoionization cross-section measurements of ${\mathrm{Rb}}^{2+}$ ions: experiment and theory (2016J. Phys. B: At. Mol. Opt. Phys.49235002) [PDF]

, 2017
David Macaluso, Kyren Bogolub, Andrea Johnson, A. Aguilar, A. L. D. Kilcoyne, R. C. Bilodeau, M. A. Bautista, Austin Kerlin, N. C. Sterling   +8 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source