Results 181 to 190 of about 161,336 (310)

Challenge of studies on the development of new Zn complexes (Zn(opt)2) to treat diabetes mellitus [PDF]

, 2011
Yutaka Yoshikawa, Akito Murayama, Yusuke Adachi, Hiromu Sakurai, Hiroyuki Yasui   +4 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Humans optimally integrate cutaneous and proprioceptive cues in haptic size perception. [PDF]

Front Hum Neurosci
Allen KS, Goldreich D.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Acute Care Research Requires an Adapted Consent Procedure to Safeguard Participants' Autonomy and Rights While Limiting the Risk of Consent-Bias. [PDF]

Acad Emerg Med
Westerhof SO, Hincapié-Osorno C, van Wijk RJ, Ter Avest E, van Munster BC, Ter Maaten JC, Bouma HR.   +6 more
europepmc   +1 more source

Peer Review Report For: Assessing the Influence of Innovation Characteristics on the Implementation Process of an Optimised Tuberculosis Diabetes Integrated Care Package (Opt TBD) -A Mixed Method Study Protocol [version 2; peer review: 1 approved, 1 approved with reservations]

Falak Pahwa
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Erratum: Assessment of skin fibrosis in a murine model of systemic sclerosis with multifunctional optical coherence tomography (Erratum). [PDF]

J Biomed Opt
Singh Chawla H, Chen Y, Wu M, Nikitin P, Gutierrez J, Mohan C, Singh M, Aglyamov SR, Assassi S, Larin KV.   +9 more
europepmc   +1 more source

Penerapan Lightning Search Algorithm dengan 2-Opt Local Search untuk Penyelesaian Asymmetric Traveling Salesman Problem

Yulius Chandra Gunawan, Ignatius A. Sandy   +1 more
openalex   +2 more sources