Results 201 to 210 of about 161,336 (310)

Erratum: Imaging otoconia by second harmonic generation microscopy: erratum. [PDF]

Biomed Opt Express
Brittain K, Harvey M, Cisek R, Pillai S, Christie SD, Tokarz D.   +5 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Enhancing radial strength and expansion uniformity of iron-based vascular scaffolds: a numerical and experimental investigation on topological optimization. [PDF]

Front Bioeng Biotechnol
Qiu J, Tang L, Fu W, Qin L, Zhang D, Wang S, Song J.   +6 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Towards best practice recommendations: Perspectives from Australian GPs to inform the use of general practice data for research - A modified Delphi study. [PDF]

Eur J Gen Pract
Green H, Beilby J, Degeling C, Adams C, Flack F, Carolan L, Fabrianesi B, Brown A, Nettel Aguirre A, Clarke A, Jung C, Braunack-Mayer A.   +11 more
europepmc   +1 more source

When to opt for preemptive anticoagulation with SARS-CoV-2 infection in the long-term care facilities

, 2022
Nadia Mujahid, Ashna Rajan, Yasin Abul, Naga Venkata Rama Krishna Vura, Iva Neupane, Kerry L. LaPlante, Stefan Gravenstein   +6 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Origin Variants of the Ascending Pharyngeal Artery and Sequential External Carotid Branching Classification. [PDF]

Diagnostics (Basel)
Calotă RN, Vrapciu AD, Hostiuc S, Rusu MI, Tudose RC, Tudosie MS, Triantafyllou G, Piagkou M, Rusu MC.   +8 more
europepmc   +1 more source

Opting in and Opting out of (Proto-)Urbanism:The integration and Disintegration of Hamoukar during the Late Chalcolithic 1 and 2 periods (4500-3900 BC)

Khaled Abu Jayyab
openalex   +1 more source

Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis [PDF]

, 2015
Leandro Venturutti, Lucía V. Romero, Alejandro J. Urtreger, María F. Chervo, Rosalía I. Cordo Russo, María F. Mercogliano, Gloria Inurrigarro, Matías G. Pereyra, Cecilia J. Proietti, Franco Izzo, María C. Díaz Flaqué, Victoria Sundblad, Juan Carlos Roa, Pablo Guzmán, Elisa Bal de Kier Joffé, Eduardo H. Charreau, Roxana Schillaci, Patricia V. Elizalde   +17 more
openalex   +1 more source