Results 231 to 240 of about 990,944 (268)

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Design and Usability of a Digitalized Compensatory Goal Management Training for Individuals with Brain Injury: A User-Centered Approach. [PDF]

Int J Telerehabil
Verhoog EM, Kessels RPC, Fasotti L, Bertens D.   +3 more
europepmc   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Neurodevelopmental disorders: assessing and training working memory. [PDF]

BMC Psychol
Ferreira P, David C, Costescu C, Vera L, Herrera G, Lopes S, Stilwell D, Ferreira A, Domingues D, Brito J, Campos J, Paiva AM, Simão AMV, Heldal I, Stefanut T, Rosan A, Trindade F.   +16 more
europepmc   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of TCE‐secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

Where age doesn't matter: no relative age effects in esports at the professional level. [PDF]

Front Sports Act Living
Laxdal A, Erikstad MK.
europepmc   +1 more source

Games and Creativity: A Theoretical Framework. [PDF]

J Intell
Mercier M, Bourgeois-Bougrine S, Lubart T.   +2 more
europepmc   +1 more source

ON THE LEARNING ALGORITHM OF 2-PERSON ZERO-SUM MARKOV GAME

ON THE LEARNING ALGORITHM OF 2-PERSON ZERO-SUM MARKOV GAME
openaire  

Beyond the joystick: deep learning games for hand movement recovery. [PDF]

Front Rehabil Sci
Acharya V, Roy H, Kamath S, Acharya K A.
europepmc   +1 more source

A method of finding all equilibrium solutions of a 2-person matrix game

, 1989
openaire   +1 more source