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PROGRESS IN THE CHEMISTRY OF 2-PYRONES

Russian Chemical Reviews, 1967
CONTENTS I. Introduction 175 II. Methods of synthesis of 2-pyrones 175 III.
N P Shusherina   +3 more
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2-Pyrones possessing antimicrobial and cytotoxic activities

Bioorganic & Medicinal Chemistry, 2004
The 2-pyrone sub-unit is found in a number of natural products possessing broad spectrum biological activity. Such compounds are validated as being capable of binding to specific protein domains and able to exert a remarkable range of biological effects.
Ian J S, Fairlamb   +4 more
openaire   +2 more sources

Pyridine-2-thiones, 2-pyrone phenylhydrazones, and 2-pyridones from 2-pyrones

Journal of the Chemical Society C: Organic, 1971
Various 5-aryloxypyran-2-thiones, 2-pyridones, and 1-amino-2-pyridones have been prepared. The pyran-2-thiones were converted into pyridine-2-thiones and phenylhydrazones. Some derivatives of 6-p-bromophenyl-5-phenoxy-4-phenyl-2-pyrone (Ia) are described.
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Substituted 2‐Pyrones and 5,6‐Dihydropyrones

Journal of Heterocyclic Chemistry, 1985
AbstractA series of substituted 2‐pyrones and 5,6‐dihydropyrones have been synthesized and investigated for their inhibitory activity toward human leukocyte elastase, procine pancreatic elastase and chymotrypsin.
William C. Groutas   +4 more
openaire   +1 more source

Asymmetric Hydrogenation of Substituted 2-Pyrones

The Journal of Organic Chemistry, 1999
Various substituted 2-pyrones have been hydrogenated with high enantioselectivity (up to 97% ee) to the corresponding 5,6-dihydropyrones using cationic ruthenium catalysts containing the (6,6‘-dimethoxybiphenyl-2,2‘diyl)bis[3,5-di(tert-butyl)phenylphosphine] ligand. When substituents at position 3 are absent, 5,6-dihydropyrones are further hydrogenated
Matthias J. Fehr   +3 more
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Iodination of 6-aryl-2-pyrones

Chemistry of Heterocyclic Compounds, 1984
The iodination of 6-aryl-2-pyrones with iodine chloride in glacial acetic acid leads to the corresponding 3-iodo derivatives. 3-Cyano-6-phenyl-2-pyrone and 3-phenylethynyl-6-phenyl-2-pyrone were obtained by replacement of the iodo group by cyano and phenylethynyl groups.
S. V. Sokolovskaya, L. K. Moldovanova
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One step preparation of bromo-2-pyrones via bromo-decarboxylation of 2-pyrone-carboxylic acids

Tetrahedron Letters, 2001
Abstract Synthetically valuable 3-bromo-2-pyrone, 3-bromocoumarin, 5-bromo-2-pyrone, and 3,5-dibromo-2-pyrone were prepared in one step from readily available 2-pyrone-carboxylic acids via bromo-decarboxylation in good to fair yields.
Cheon-Gyu Cho   +3 more
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3-Hydroxy-2-pyrone

2001
[496-64-0] C5H4O3 (MW 112.09) InChI = 1S/C5H4O3/c6-4-2-1-3-8-5(4)7/h1-3,6H InChIKey = LIPRKYKMVQPYPG-UHFFFAOYSA-N ([4 + 2] cycloaddition vinylketene diene equivalent2, 3) Physical Data: white, crystalline solid; mp 92 °C; mp (dihydrate) 80–85 °C; bp 112 °C/20 mmHg; sublimes at 50 °C/4 mmHg; λmax 294 nm (H2O ...
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Synthesis of 5,6-Dihydro-2-pyrone and 2-Pyrone

Synthesis, 1974
Masako NAKAGAWA   +5 more
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2-Pyrones. VII. 2-Pyridones from 2-Pyrones

Journal of the American Chemical Society, 1954
Richard H. Wiley   +3 more
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