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PROGRESS IN THE CHEMISTRY OF 2-PYRONES
Russian Chemical Reviews, 1967CONTENTS I. Introduction 175 II. Methods of synthesis of 2-pyrones 175 III.
N P Shusherina +3 more
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2-Pyrones possessing antimicrobial and cytotoxic activities
Bioorganic & Medicinal Chemistry, 2004The 2-pyrone sub-unit is found in a number of natural products possessing broad spectrum biological activity. Such compounds are validated as being capable of binding to specific protein domains and able to exert a remarkable range of biological effects.
Ian J S, Fairlamb +4 more
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Pyridine-2-thiones, 2-pyrone phenylhydrazones, and 2-pyridones from 2-pyrones
Journal of the Chemical Society C: Organic, 1971Various 5-aryloxypyran-2-thiones, 2-pyridones, and 1-amino-2-pyridones have been prepared. The pyran-2-thiones were converted into pyridine-2-thiones and phenylhydrazones. Some derivatives of 6-p-bromophenyl-5-phenoxy-4-phenyl-2-pyrone (Ia) are described.
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Substituted 2‐Pyrones and 5,6‐Dihydropyrones
Journal of Heterocyclic Chemistry, 1985AbstractA series of substituted 2‐pyrones and 5,6‐dihydropyrones have been synthesized and investigated for their inhibitory activity toward human leukocyte elastase, procine pancreatic elastase and chymotrypsin.
William C. Groutas +4 more
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Asymmetric Hydrogenation of Substituted 2-Pyrones
The Journal of Organic Chemistry, 1999Various substituted 2-pyrones have been hydrogenated with high enantioselectivity (up to 97% ee) to the corresponding 5,6-dihydropyrones using cationic ruthenium catalysts containing the (6,6‘-dimethoxybiphenyl-2,2‘diyl)bis[3,5-di(tert-butyl)phenylphosphine] ligand. When substituents at position 3 are absent, 5,6-dihydropyrones are further hydrogenated
Matthias J. Fehr +3 more
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Iodination of 6-aryl-2-pyrones
Chemistry of Heterocyclic Compounds, 1984The iodination of 6-aryl-2-pyrones with iodine chloride in glacial acetic acid leads to the corresponding 3-iodo derivatives. 3-Cyano-6-phenyl-2-pyrone and 3-phenylethynyl-6-phenyl-2-pyrone were obtained by replacement of the iodo group by cyano and phenylethynyl groups.
S. V. Sokolovskaya, L. K. Moldovanova
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One step preparation of bromo-2-pyrones via bromo-decarboxylation of 2-pyrone-carboxylic acids
Tetrahedron Letters, 2001Abstract Synthetically valuable 3-bromo-2-pyrone, 3-bromocoumarin, 5-bromo-2-pyrone, and 3,5-dibromo-2-pyrone were prepared in one step from readily available 2-pyrone-carboxylic acids via bromo-decarboxylation in good to fair yields.
Cheon-Gyu Cho +3 more
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2001
[496-64-0] C5H4O3 (MW 112.09) InChI = 1S/C5H4O3/c6-4-2-1-3-8-5(4)7/h1-3,6H InChIKey = LIPRKYKMVQPYPG-UHFFFAOYSA-N ([4 + 2] cycloaddition vinylketene diene equivalent2, 3) Physical Data: white, crystalline solid; mp 92 °C; mp (dihydrate) 80–85 °C; bp 112 °C/20 mmHg; sublimes at 50 °C/4 mmHg; λmax 294 nm (H2O ...
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[496-64-0] C5H4O3 (MW 112.09) InChI = 1S/C5H4O3/c6-4-2-1-3-8-5(4)7/h1-3,6H InChIKey = LIPRKYKMVQPYPG-UHFFFAOYSA-N ([4 + 2] cycloaddition vinylketene diene equivalent2, 3) Physical Data: white, crystalline solid; mp 92 °C; mp (dihydrate) 80–85 °C; bp 112 °C/20 mmHg; sublimes at 50 °C/4 mmHg; λmax 294 nm (H2O ...
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Synthesis of 5,6-Dihydro-2-pyrone and 2-Pyrone
Synthesis, 1974Masako NAKAGAWA +5 more
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2-Pyrones. VII. 2-Pyridones from 2-Pyrones
Journal of the American Chemical Society, 1954Richard H. Wiley +3 more
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