Results 131 to 140 of about 13,725,004 (318)
St Lukes and St Matthews, OSV-0003013, 20 September 2018
Inspection date: 2018-09 ...
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
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The study investigated the usefulness of hydrodynamic cavitation (HC) in removing polycyclic aromatic hydrocarbons (PAHs) from a highly polluted car-wash wastewater.
Agnieszka Montusiewicz +3 more
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State of the U.S. economy [PDF]
Address before AAIM Management Association, St. Louis, Mo., Feb. 20, 2004Economic conditions - United States ; Inflation (Finance)
William Poole
core
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Mechanical Properties of Li-Nb-O System Films
Objective: To quantitatively assess the hardness, elasticity, and plasticity, and to determine the influence of structure and substructure on these parameters in Li-Nb-O system films. Experimental: Li-Nb-O system films with a thickness of ~0.8 μm were
Aleksandr V. Kostyuchenko +5 more
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Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Proučavanje čakavskih govora u 20. st.
U članku su naznačene tematika i metodologija proučavanja čakavskih govora u 20. st. Kraći je osvrt dan na radove s početka stoljeća, kada su istraživanja bila usmjerena na taksativno nabrajanje razlikovnosti govora određenog areala u odnosu na hrvatski standardni sustav, a podaci nesistematizirani. Veća je pozornost posvećena drugoj polovici 20.
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