Results 131 to 140 of about 13,725,004 (318)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Effects of hydrodynamic cavitation in removal of polycyclic aromatic hydrocarbons (PAHs) from car-wash wastewater

open access: yesDesalination and Water Treatment
The study investigated the usefulness of hydrodynamic cavitation (HC) in removing polycyclic aromatic hydrocarbons (PAHs) from a highly polluted car-wash wastewater.
Agnieszka Montusiewicz   +3 more
doaj   +1 more source

Metastatic Low‐Grade Gliomas in Children: 20 Years' Experience at St. Jude Children's Research Hospital

open access: yesPediatric Blood & Cancer, 2016
Omar Chamdine   +4 more
semanticscholar   +1 more source

State of the U.S. economy [PDF]

open access: yes
Address before AAIM Management Association, St. Louis, Mo., Feb. 20, 2004Economic conditions - United States ; Inflation (Finance)
William Poole
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Mechanical Properties of Li-Nb-O System Films

open access: yesКонденсированные среды и межфазные границы
Objective: To quantitatively assess the hardness, elasticity, and plasticity, and to determine the influence of structure and substructure on these parameters in Li-Nb-O system films. Experimental: Li-Nb-O system films with a thickness of ~0.8 μm were
Aleksandr V. Kostyuchenko   +5 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Proučavanje čakavskih govora u 20. st.

open access: yes, 2006
U članku su naznačene tematika i metodologija proučavanja čakavskih govora u 20. st. Kraći je osvrt dan na radove s početka stoljeća, kada su istraživanja bila usmjerena na taksativno nabrajanje razlikovnosti govora određenog areala u odnosu na hrvatski standardni sustav, a podaci nesistematizirani. Veća je pozornost posvećena drugoj polovici 20.
openaire   +1 more source

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