Results 101 to 110 of about 19,214,587 (391)
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
, 2001 Llegó el 2000 y no hubo el caos informático que tanto se había vaticinado. La voz de alarma había partido desde los gobiernos, las empresas y organizaciones del mundo entero que alertaban sobre el cambio de fecha del siglo y que se le empezaba a conocer como Efecto 2000 (Y2K o “Millenium Bug”).
openaire +1 more source
The domestic adjusted monetary base [PDF]
This paper provides a consistent, monthly measure of the amount of the U.S. adjusted monetary base that is domestically held, and of the amount held abroad.
Richard G. Anderson, Robert H. Rasche
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Archaic Sculpturings: Notes on Art, Philosophy, and Religion in Britain, 2000 BC to 900 AD [PDF]
, 1916 openalex +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Discussion on ``Development of a Successful Direct-Current 2000-kw. Unipolar Generator'' (Lamme), Boston, Mass., June 28, 1912 [PDF]
, 1912 J. E. Noeggerath
openalex +1 more source
The temporal pattern of trading rule returns and central bank intervention: intervention does not generate technical trading rule profits [PDF]
This paper characterizes the temporal pattern of trading rule returns and official intervention for Australian, German, Swiss and U.S. data to investigate whether intervention generates technical trading rule profits.
Christopher J. Neely
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Rückblick auf 2000 Operationen wegen Appendicitis1) [PDF]
, 1909 Julius Schnitzler
openalex +1 more source