Biomass burning, PM2.5 peaks, and trends in lung adenocarcinoma diagnoses: an ecological study in São Paulo State, Brazil. [PDF]
Silva SB, Larssen HG, Colli LM.
europepmc +1 more source
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Chemical Composition and Bioactivities of Turkish <i>Leonurus</i> Species (Lamiaceae) Extracts: Antioxidant, Antimicrobial, and Antiproliferative Potential. [PDF]
Saltan N +4 more
europepmc +1 more source
Xenotransplantation—2000 [PDF]
M J, Goddard +2 more
openaire +2 more sources
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer +4 more
wiley +1 more source
Global, regional and national burden of maternal haemorrhage (2000-2021) and projections to 2050 in 204 countries and territories. [PDF]
Ayele M +15 more
europepmc +1 more source
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1–8) assigned to each domain.
Kevin Zhang +8 more
wiley +1 more source
Oophorectomy-Corrected Ovarian Cancer Incidence, Survival, and Mortality by Subtype, Race, Ethnicity. [PDF]
Wentzensen N +4 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Provincial Trends in Childhood Vaccine Coverage in Afghanistan From 2000 to 2024: An Ecological Study of Findings From the Institute for Health Metrics and Evaluation. [PDF]
Khan A, Tidman M.
europepmc +1 more source

