Results 11 to 20 of about 6,543,566 (246)

THE FRENCH MUNICIPAL AND EUROPEAN ELECTIONS, 2014 [PDF]

open access: yes, 2014
© 2014, McDougall Trust, London. This article examines the 2014 French municipal and European elections, which were effectively mid-term contests for President François Hollande and the Socialist Party, held in the context of a poor economic situation ...
Kuhn, R
core   +1 more source

The 2014 International Planning Competition: Progress and Trends [PDF]

open access: yes, 2015
We review the 2014 International Planning Competition (IPC-2014), the eighth in a series of competitions starting in 1998. IPC-2014 was held in three separate parts to assess state-of-the-art in three prominent areas of planning research: the ...
Chrpa, Lukáš   +14 more
core   +2 more sources

A century of sea level data and the UK's 2013/14 storm surges: an assessment of extremes and clustering using the Newlyn tide gauge record [PDF]

open access: yes, 2014
For the UK's longest and most complete sea level record (Newlyn), we assess extreme high waters and their temporal clustering; prompted by the 2013/2014 winter of storms and flooding. These are set into context against this almost 100-year record.
M. P. Wadey   +7 more
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Universities: 2014 audit snapshot [PDF]

open access: yes, 2015
This report sets out the key outcomes from financial audits of the eight universities and their 51 controlled entities for the year ending 31 December 2014.
Victorian Auditor-General
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Examination of legislation in accordance with the Human Rights (Parliamentary Scrutiny) Act 2011: Bills introduced 17 – 20 March 2014, Legislative Instruments received 1 – 7 March 2014 [PDF]

open access: yes, 2014
This report examines the human rights compatibility of bills recently introduced into Parliament. Executive summary This report provides the Parliamentary Joint Committee on Human Rights\u27 view on the compatibility with human rights as defined in the

core  

Managing open access (OA) workflows at the University of St Andrews: challenges and Pathfinder solutions [PDF]

open access: yes, 2014
© 2014. Janet Aucock. This is an open access article distributed under the Creative Commons Attribution Licence, which permits unrestricted use and distribution provided the original author and source are credited.This article arose out of a presentation
Janet Aucock, Aucock, Janet
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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