Results 71 to 80 of about 4,146,693 (295)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Comment on egusphere-2022-78 [PDF]

open access: gold, 2022
Pfreundschuh, Simon   +4 more
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Exploring and determining traditional medicines used for bleeding control and termination of pregnancy among Suri people, South West Ethiopia, 2022: mixed method exploratory sequential study design

open access: yesBMC Complementary Medicine and Therapies
Background The treatment of severe bleeding, stopping pregnancies, and other gynecologic conditions have all been addressed by women using traditional medicines and methods.
Alemnew Wale   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Editorial: Case reports in general cardiovascular medicine: 2022

open access: yesFrontiers in Cardiovascular Medicine, 2023
Lijun Wang   +5 more
doaj   +1 more source

RWW 2022 Workshops [RWW 2022] [PDF]

open access: yesIEEE Microwave Magazine, 2021
Vaclav Valenta, Venkata Vanukuru
openaire   +1 more source

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