Results 111 to 120 of about 11,217,492 (290)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

بررسی شيوع نسبت فاميلی والدين در کودکان دچار کاهش شنوايی مراجعه کننده به مراکز توانبخشی سازمان بهزيستی ايران [PDF]

, 2006
زمينه و هدف: ازدواج‌های فاميلی در بسياری از جوامع بشری صورت می‌گيرند. در اکثر مناطق جنوب آسيا، والدين 50-20% از متولدين نسل حاضر، دارای نسبت فاميلی می‌باشند. تاثير ازدواج فاميلی در کم شنوايی‌های ارثی، بخوبی، مطالعه و ثبت شده است.
جعفری, زهرا, لطفی, یونس, مهرکيان, سعیده   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Low dose deltamethrin exposure affects gene expression in rat frontal cortex

Translation
Pyrethroids are a class of commonly used synthetic insecticides, widely used in agricultural and residential settings due to their efficacy and relatively low environmental impact.
Junze Wu, Ariv Shah, Rami Ridi, Zacharia Rashid, Ali Sajid Imami, Nilanjana Saferin, James Patrick Burkett   +6 more
doaj   +1 more source

Analyzing Customer Preference Towards Payment System: Cash, Debit Card and Credit Card [PDF]

, 2014
Payment system is a tool of payment that purposes to help activity of buyer and seller transaction easier. In this modern area it is required to the instrument payment which easier to bring and practical for usage.
Pomantow, M. P. (Marselina)
core  

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Divine Holiness as Absolute Love: Hans Urs von Balthasar on the Holiness of the Trinitarian Life

Perichoresis: The Theological Journal of Emanuel University
This essay will consider the holiness of God through the lens of divine love, as is appropriate when following the contours of the theology of Hans Urs von Balthasar.
Crickenberger Cameron
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

From Citizen Science to Human Security: A tool to facilitate Members of Parliaments’ engagement with constituents

Cadmus
Citizen science tools can demonstrate the transformative potential of citizen engagement as a catalyst for structural change and democratisation within society.
Denis Naughten
doaj