Results 31 to 40 of about 2,511,182 (316)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Humanitarian diplomacy strategy of Spain 2023-2026 [PDF]
, 2023 Tras la creación en 2007 de la Oficina de Acción Humanitaria y la aprobación en 2019 de la Estrategia de Acción Humanitaria de la Cooperación Española 2019-2026, la Estrategia que aquí se presenta se concibe como una herramienta para fortalecer la ...
Agencia Española de Cooperación Internacional para el Desarrollo. Oficina de Acción Humanitaria +2 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Lääkkeen käyttäjä lääkeinformaation keskiöön : Kansallinen lääkeinformaatiostrategia 2021‒2026 [PDF]
, 2021 Päämäärä Vuoden 2026 loppuun mennessä järkevää lääkehoitoa edistetään Suomessa luotettavan lääkeinformaation avulla sosiaali- ja terveydenhuollon ammattihenkilöiden ja lääkkeen käyttäjien välisessä tiiviissä yhteistyössä, jossa lääkkeen käyttäjien ja ...
Kiviranta, Päivi +1 more
core
Nucleic Acids ResearchAbstract The Ensembl project (https://www.ensembl.org) is a public and open resource providing access to genomes, annotations, high-quality tools, and methods applicable to species from across the tree of life. This year has witnessed nearly a doubling in our rate of annotation and genome release, with 1927 new genomes released, with ...
Andrew D Yates +84 more
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source