Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]
We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
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Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi+6 more
wiley +1 more source
Expression of murine 21-hydroxylase in mouse adrenal glands and in transfected Y1 adrenocortical tumor cells. [PDF]
K L Parker+5 more
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Serotonergic modulators in Alzheimer's disease: a hope in the hopeless condition
Alzheimer disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Ali I. Al-Gareeb+5 more
wiley +1 more source
The Coexistence of IgA Deficiency and 21‐Hydroxylase Deficiency Marked by Specific MHC Supratypes [PDF]
T.J. Cobain+7 more
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Characterization of the Cubamyces Menziesii Terpenome
The genome of Cubamyces menziesii reveals 18 putative sesquiterpene cyclase genes. These genes are cloned and expressed in Escherichia coli, yielding 10 active enzymes. Using farnesyl diphosphate as substrate, the enzymes are analyzed, and the products characterized after bioconversion, uncovering diverse sesquiterpene structures. This study highlights
Létitia Leydet+10 more
wiley +1 more source
Métabolisme des glucocorticoïdes dans le poumon murin en développement : la voie surrénalienne [PDF]
Lorsqu’une femme est à risque d’accoucher prématurément, des glucocorticoïdes lui seront administrés afin d’accélérer la maturation pulmonaire du bébé.
Gilbert, Catherine
core
Immunohistochemical demonstration of steroid C-21 hydroxylase in normal and neoplastic salivary glands [PDF]
Hironobu Sasano+2 more
openalex +1 more source
Pioneering Women Shaping the Field of Biocatalysis
Groundbreaking works of women scientists in biocatalysis are highlighted in this article. Their innovative contributions are categorized in four interrelated research areas, collectively driving advancements in enzymatic biotransformations. Abstract In this perspective article, we celebrate the accomplishments of female‐led research groups in ...
Ana I. Benítez‐Mateos+3 more
wiley +1 more source
Congenital adrenal hyperplasia: The influence of puberty on cortisol pharmacokinetics. [PDF]
In Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency, appropriate glucocorticoid substitution does not often result in adequate suppression of the hypothalamic-pituitary-adrenal (HPA) axis. Suboptimal control is especially observed in
Charmandari, Evangelia
core