Results 191 to 200 of about 2,389,640 (367)

Exploring the Role of T‐Cell Metabolism in Modulating Immunotherapy Efficacy for Non‐Small Cell Lung Cancer Based on Clustering

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We conducted a comprehensive investigation of the metabolic profiles of infiltrating T cells in NSCLC tumors and found metabolic heterogeneity in three T‐cell subtypes, which are associated with the prognosis of ICB therapy. We defined these metabolic clusters as response‐dependent (R) clusters and non‐response‐dependent (NR) clusters, and elucidated ...
Hongzhe Guo   +7 more
wiley   +1 more source

Production of hydroxyectoine from biogas by an engineered strain of Methylomicrobium alcaliphilum using a novel Taylor‐flow bioreactor

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The production of compatible solutes, such as ectoine and hydroxyectoine, is of great interest due to their industrial and biotechnological applications. Methylomicrobium alcaliphilum was genetically engineered to replace a native gene with a heterologous one, aiming to enhance ectoine production.
Raquel Herrero‐Lobo   +7 more
wiley   +1 more source

Sensory and Autonomic Fibers in Anterior Ethmoid, Posterior Nasal, Posterolateral Nasal Nerves

open access: yesThe Laryngoscope, EarlyView.
All cadaveric anterior ethmoid, posterior, and posterolateral nasal nerves contained roughly equivalent proportions of sensory, parasympathetic, and sympathetic nerve fiber markers. Neurokinin A was the only neuropeptide with consistently greater percent areas across the different nasal nerves.
John R. Craig   +6 more
wiley   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu   +10 more
wiley   +1 more source

Neonatal Screening for Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

open access: bronze, 1986
Masaru Fukushi   +5 more
openalex   +2 more sources

Steroid 21-Hydroxylase Autoantibodies: Measurements with a New Immunoprecipitation Assay1 [PDF]

open access: bronze, 1997
Hideaki Tanaka   +11 more
openalex   +1 more source

Myoclonic Dystonia: A Common Phenomenology in the Pleomorphic Movements of Angelman Syndrome

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Angelman syndrome (AS) is a neurodevelopmental disorder characterized by developmental delay, intellectual disability, a sociable demeanor, and abnormal movements. People with AS often exhibit multiple types of abnormal movements, including nonepileptic myoclonus, tremor, and dystonia, which hamper attempts to identify phenomenology
Robert P. Carson   +8 more
wiley   +1 more source

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