Results 291 to 300 of about 2,389,640 (367)

The gut‐microbiota‐brain axis: Focus on gut steroids

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract There are over 1000 varieties of steroids that have been reported in nature, including the endogenous sex steroid hormones (i.e., progesterone, testosterone, and 17β‐estradiol) and corticosteroids which are mainly synthesized by gonads and adrenals, respectively.
Silvia Diviccaro   +4 more
wiley   +1 more source

Neuroactive steroid exposure impacts neurodevelopment: Comparison of human and rodent placental contribution

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract The placenta is a fetal endocrine organ that secretes many neuroactive factors, including steroids, that play critical roles in brain development. The study of the placenta‐brain axis and the links between placental function and brain development represents an emerging research area dubbed “neuroplacentology.” The placenta drives many ...
Claire‐Marie Vacher   +3 more
wiley   +1 more source

Obesity and hypoxia have differential effects on myocardial innervation in the right ventricle of the male mouse heart

open access: yesJournal of Anatomy, EarlyView.
Obesity induced by a high fat diet caused hyperinnervation of the right ventricle, whereas chronic hypoxia alone did not significantly alter right ventricular innervation. Surprisingly, chronic hypoxia attenuated the obesity‐induced changes in right ventricular innervation.
Louisa‐Chiara Mierswa   +2 more
wiley   +1 more source

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca   +2 more
wiley   +1 more source

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