Results 51 to 60 of about 804,749 (296)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Management of spot blotch using fungicidal combinations in wheat (Triticum aestivum)

The Indian Journal of Agricultural Sciences
Spot blotch is a major constraint to wheat (Triticum aestivum L.) production in the Eastern Gangetic Plains (EGP) of India, where wheat cultivars express moderate resistance to susceptible reaction. Limited information available on yield penalties under
UDAY KUMAR, C S AZAD, AMARENDRA KUMAR, SANJEEV KUMAR, DEEPAK KUMAR BARANWAL   +4 more
doaj   +1 more source

Numerical Exploratory Analysis of Dynamics and Control of an Atomic Force Microscopy in Tapping Mode with Fractional Order

Shock and Vibration, 2020
In this paper, we investigate the mechanism of atomic force microscopy in tapping mode (AFM-TM) under the Casimir and van der Waals (VdW) forces.
Mauricio A. Ribeiro, Jose M. Balthazar, Wagner B. Lenz, Rodrigo T. Rocha, Angelo M. Tusset   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Expression of miR-210-3p in the aqueous humor of patients with age-related cataracts and its effect on human lens epithelial cell injury induced by hydrogen peroxide [PDF]

, 2023
Purpose: The regulatory effect of microRNA on diseases has been confirmed. This study aimed to evaluate the expression of microRNA-210-3p in age-related cataracts and assess the effect of abnormal miR-210-3p expressions on H2O2-induced SAR01/04 cells ...
Famang Zheng (15311765), Xiangfeng Lou (15311768), Jianping Xu (163726), Wenlong Zhang (283123), Chen Xu (53797)   +4 more
core   +1 more source

Effect of harvesting time and desapping on sapburn and quality in mango (Mangifera indica) cv. Langra

The Indian Journal of Agricultural Sciences, 2015
Sapburn is one of the most important problems in mango (Mangifera indica L.) which severely downgrade its quality and reduces its market value. In the present study, two experiments were conducted to study the effect of harvesting time on sap flow ...
KALYAN BARMAN, V B PATEL, R R SINGH, MUNESHWAR PRASAD, PUSHPA KUMARI   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Image_1_MicroRNA-210-3p Targets RGMA to Enhance the Angiogenic Functions of Endothelial Progenitor Cells Under Hypoxic Conditions.tif [PDF]

, 2019
Endothelial progenitor cells (EPCs) are multipotential stem cells considered to have immense clinical value for revascularization. However, the clinical application of EPCs has been hampered by their clinical potency in ischemic anoxic environments. This
Li-Li Zeng (6716543), Kai-Qi Ding (6716537), Guo-Yuan Yang (178975), Xiao-Yu Xin (6716540), Xuan-Qiang Tu (6716531), Wen-Jing Lu (6716525), Huai-Bin Liang (6716528), Yong-Fang Li (1987822), Ji-Rong He (6716534)   +8 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Data_Sheet_1_MicroRNA-210-5p Contributes to Cognitive Impairment in Early Vascular Dementia Rat Model Through Targeting Snap25.docx [PDF]

, 2018
Vascular dementia (VD) is the most common form of dementia in elderly people. However, little is understood about the role of microRNAs (miRNAs) involved in cognitive impairment in early VD. Here, a VD model induced by chronic cerebral ischemia and fetal
Yuqing Liu (103879), Rudong Deng (5907641), Wenwen Si (5956190), Jianhong Zhou (1528570), Dongfeng Chen (405191), Zhenxing Ren (4860955), Xianqian Li (5956193), Zimei Wu (4802982), Junlong Yu (5956187)   +8 more
core   +1 more source