Results 31 to 40 of about 42,411 (250)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Flow Cytometry Analysis of Antibacterial Effects of Universal Dentin Bonding Agents on Streptococcus mutans

Molecules, 2019
There is no consensus on the antibacterial activity of dentin bonding systems (DBS). Many study models have been used to evaluate the antimicrobial activity of dental materials. In this study, a novel detection method, flow cytometry, was introduced.
Barbara Lapinska, Magdalena Konieczka, Beata Zarzycka, Krzysztof Sokolowski, Janina Grzegorczyk, Monika Lukomska-Szymanska   +5 more
doaj   +1 more source

An Extensive Review and Comparison of Modern Biomass Torrefaction Reactors vs. Biomass Pyrolysis—Part 1

Energies, 2022
Major efforts are currently being made in the research community to address the challenges of greenhouse gas emissions from fossil fuel combustion by using lignocellulosic biomass, agricultural waste, and forest residues as cleaner energy sources ...
Piotr Piersa, Hilal Unyay, Szymon Szufa, Wiktoria Lewandowska, Remigiusz Modrzewski, Radosław Ślężak, Stanisław Ledakowicz   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Phytotherapy for Acne Vulgaris - a Review

Journal of Education, Health and Sport
Introduction and Purpose: Acne vulgaris, a chronic inflammatory skin condition, primarily affects adolescents and young adults, causing non-inflammatory and inflammatory lesions.
Adrianna Kruczkowska, Mateusz Pakuła, Wojciech Urbański, Natalia Dolata, Agnieszka Cebula, Emil Bulzacki, Aleksandra Stosiek, Bartosz Balcer, Andrzej Kanturski, Paweł Liszka   +9 more
doaj   +1 more source

Fibroblast Growth Factor 23 and Cardiovascular Risk in Diabetes Patients—Cardiologists Be Aware

Metabolites, 2022
Numerous clinical studies have indicated that elevated FGF23 (fibroblast growth factor 23) levels may be associated with cardiovascular (CV) mortality, especially in patients with chronic kidney disease.
Anna Kurpas, Karolina Supel, Paulina Wieczorkiewicz, Joanna Bodalska Duleba, Marzenna Zielinska   +4 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Isolation, Characterization, and RP-HPLC Estimation of P-Coumaric Acid from Methanolic Extract of Durva Grass (Cynodon dactylon Linn.) (Pers.)

International Journal of Analytical Chemistry, 2015
P-coumaric acid is a nonflavonoid phenolic acid and is a major constituent of the species Cynodon dactylon Linn. (Pers.). In this study isolation of P-coumaric acid was achieved by preparative TLC and the compound thus isolated was characterised by UV ...
Ramadoss Karthikeyan, Chapala Devadasu, Puttagunta Srinivasa Babu   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection

Beilstein Journal of Nanotechnology, 2016
Proteases, including matrix metalloproteinases (MMPs), tissue serine proteases, and cathepsins (CTS) exhibit numerous functions in tumor biology. Solid tumors are characterized by changes in protease expression levels by tumor and surrounding tissue ...
Dinusha N. Udukala, Hongwang Wang, Sebastian O. Wendel, Aruni P. Malalasekera, Thilani N. Samarakoon, Asanka S. Yapa, Gayani Abayaweera, Matthew T. Basel, Pamela Maynez, Raquel Ortega, Yubisela Toledo, Leonie Bossmann, Colette Robinson, Katharine E. Janik, Olga B. Koper, Ping Li, Massoud Motamedi, Daniel A. Higgins, Gary Gadbury, Gaohong Zhu, Deryl L. Troyer, Stefan H. Bossmann   +21 more
doaj   +1 more source