Results 31 to 40 of about 119,578 (265)
Advanced Science, EarlyView.Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu +5 more
wiley +1 more source
Neurobiology of Disease, 2006 DJ-1 has recently been shown to be responsible for onset of familial Parkinson’s disease (PD), PARK7. DJ-1 has been shown to play roles in transcriptional regulation and anti-oxidative stress, and loss of its function is thought to trigger onset of PD ...
Masatoshi Inden +15 more
doaj +1 more source
Halide Perovskite: A Rich Source of Thermal Insulator
Advanced Science, EarlyView.Halide perovskites exhibit ultralow thermal conductivity driven by intrinsic lattice softness and strong anharmonicity, falling below conventional defect‐engineering limits. Weak metavalent bonding, A‐site rattling, and dynamic octahedral tilting drive phonon scattering to the Ioffe–Regel limit, where wave‐like tunneling replaces particle‐like ...
Haolin Ye +3 more
wiley +1 more source
Advanced Science, EarlyView.This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley +1 more source
Cost Pass‐Through in Crisis: Evidence From the German Malt‐Beer Supply Chain
Agribusiness, EarlyView.Abstract Global agri‐food supply chains are increasingly exposed to geopolitical shocks, climate volatility, and market consolidation, factors that disrupt traditional price relationships and reshape market power dynamics. Nowhere is this more visible than in the brewing sector, where agricultural raw materials meet complex industrial processing and ...
Nikolas Bublik, Lukáš Čechura
wiley +1 more source
Synoptic climatology of extratropical transition of tropical cyclones over the Southern Hemisphere [PDF]
Weather and Climate DynamicsTropical cyclones that move into the midlatitudes undergo changes in their structure and transition into extratropical cyclones. The process is known as extratropical transition (ET).
C. Jin, E. A. Ritchie, N. J. Holbrook
doaj +1 more source
Agribusiness, EarlyView.ABSTRACT Since the final decade of the 20th century, Latin American countries have increasingly regarded the signing of regional trade agreements (RTAs) as a promising strategy for expanding their exports. Within this context, the main objective of this study is to assess the impact of RTAs on agri‐food exports in Latin America over the period 1990 ...
María‐Isabel Ayuda +2 more
wiley +1 more source
Clinical Opportunities in Combining Immunotherapy with Radiation Therapy
Frontiers in Oncology, 2012 Preclinical work in murine models suggests that local radiotherapy plus intratumoral syngeneic DC injection can mediate immunologic tumor eradication. Radiotherapy affects the immune response to cancer, besides the direct impact on the tumor cells, and ...
Steven Eric Finkelstein, Mayer eFishman
doaj +1 more source
Playing in the Dark: Invisible Chess as a Laboratory for Strategic AI
AI &Innovation, EarlyView.This paper shows that strategic AI evaluated on perfect‐information benchmarks can be brittle in real adversarial settings. By using invisible chess as a benchmark for hidden state and deception, it argues for stricter testing, human oversight, and more cautious governance of high‐stakes AI systems.
Paolo Ciancarini
wiley +1 more source
BJPsych Bulletin, 2016 Phillip McGarry previously highlighted benefits of maintaining medical impartiality in an era of political dissent,[1][1] but this striving for neutrality seems vulnerable to coming unstuck when it comes to analysis of putative relationships between mental illness and terrorism.
David V, James, Jonathan, Hurlow
openaire +2 more sources