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“Moral Awareness” as an Adequate Idea in Spinoza’s Ethics: Conscious or Conscience? [PDF]

, 2022
DAĞ, Enes
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Abstract 2528: New ovarian cancer approach based on sensitizing the MDM2 inhibitor by an exportin-1 inhibitor

Cancer Research, 2023
Objective: The study is to investigate the efficacy of MDM2 inhibitor RG-7388 in combination with Selinexor on ovarian cancer cells. Background: According to the Center for Disease Control (CDC), in the United States of America, ovarian cancer is ...

semanticscholar   +1 more source

Abstract 2528: PDLIM2 expression in triple negative breast cancer stromal macrophages

Cancer Research, 2022
PDLIM2 is a PDZ-LIM domain protein expressed in hematopoietic and epithelial cells that regulates the stability of transcription factors including NFΚB, STATs and beta catenin.
O. Cox, S. Ward, E. Tresse, R. O’Connor   +3 more
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Abstract 2528: Tumor-derived exosomal miR-619-5p promotes tumor angiogenesis and metastasis through the inhibition of RCAN1.4

Molecular and Cellular Biology / Genetics, 2020
Tumor-derived exsosomes (TEXs) contain enriched miRNAs act as novel non-invasive biomarkers for cancer diagnosis, and they are involved in cancer progression.
Sangyong Jung, Dong Ha Kim, Yong-Hee Cho, Yun-Jung Choi, Seon Ye Kim, Ki Jung Sung, Chae Won Lee, H. Lee, Chang-Min Choi, Jae Cheol Lee, J. Rho   +10 more
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Abstract 2528: Determining gene expression variability betweenin vitroandin vivocancer models: Monolayer, spheroids, and mouse allografts

Molecular and Cellular Biology / Genetics, 2018
An ideal pre-clinical environment that recapitulates in vivo growth conditions ex vivo is an essential pre-requisite for effective drug screening.
N. Hum, Wei He, A. Sebastian, E. Wheeler, M. Coleman, G. Loots   +5 more
semanticscholar   +1 more source

Abstract 2528: Genomic and immune microenvironment features influencing chemoimmunotherapy response in gastric cancer with peritoneal metastasis: A retrospective cohort study

Cancer Research
Background: Patients with peritoneal metastasis (PM) from gastric cancer (GC) exhibit poor prognosis. Chemoimmunotherapy offers promising clinical benefits; however, its efficacy and predictive biomarkers in a conversion therapy setting remain unclear.
Pengfei Yu, Guangyu Ding, Xingmao Huang, Chenxuan Wang, Jingquan Fang, Ling Huang, Z. Ye, Qi Xu, Xiaoying Wu, Junrong Yan, Qiuxiang Ou, Haimeng Tang, Yi-an Du, Xiangdong Cheng   +13 more
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Development of an Injector Bracket for Precise and Efficient Fuel Spray Inspection in the Combustion Chamber of the Mercy Axor 2528 Unit at PT Antareja Mahada Makmur Site MIFA, April – July 2025

Devotion : Journal of Research and Community Service
The fuel injector system on the Mercy Axor 2528 functions to spray fuel (diesel) into the engine combustion chamber with the right amount and time, so that the combustion process runs efficiently.
Fajri Alrazzak, Nanang Sofiyulloh G
semanticscholar   +1 more source

#2528 Prognostic value of Glasgow Prognostic Score and its derived scores in patients undergoing hemodialysis

Nephrology, Dialysis and Transplantation
The Glasgow Prognostic Score (GPS), its modified version (mGPS), and the high-sensitivity mGPS (HS-mGPS) are widely recognized as effective tools for predicting outcomes in patients with cancer.
Kenta Torigoe, Emiko Otsuka, Shinichi Abe, Mineaki Kitamura, Kumiko Muta, T. Nishino   +5 more
semanticscholar   +1 more source

Abstract 2528: Bioinspired multispectral imaging for intraoperative detection of metastatic lymph nodes: enhancing precision through UV and NIR fluorescence

Cancer Research
Intraoperative identification of metastatic lymph nodes (LNs) remains a clinical challenge, with current techniques often leading to unnecessary removal of healthy tissue or retention of cancer-positive nodes.
Zhongmin Zhu, Yifei Jin, Brianna Hajek, Shuming Nie, Viktor Gruev   +4 more
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Redirecting immune signaling with cytokine adaptors 2528

Journal of Immunology
Cytokines coordinate complex immune processes but have pleiotropic effects, which limits their therapeutic utility. We devised an approach to functionalize cytokine antagonists with “adaptors” to deliver a local cytokine agonist signal through ...
Gita C. Abhiraman, K. C. Garcia
semanticscholar   +1 more source