Results 221 to 230 of about 107,165 (276)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Molecular phylogenies provide insights into the evolutionary relationships of the Spirurida (Nematoda), with special emphasis on the superfamily Physalopteroidea. [PDF]

Parasit Vectors
Sun M, Yousaf MA, Harras S, Gibson DI, Chen HX, Elmahy RA, Li L.   +6 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Description of <i>Sarcocystis arvalis</i> n. sp. from the Common Vole (<i>Microtus arvalis</i>) in Lithuania Using Morphological and Molecular Methods. [PDF]

Pathogens
Bagdonaitė DL, Rudaitytė-Lukošienė E, Stirkė V, Balčiauskas L, Butkauskas D, Prakas P.   +5 more
europepmc   +1 more source

Garden City, Village of and Village of Garden City Supervisory Unit, CSEA, Local 1000, AFSCME, AFL-CIO, Local 882 (2001) [PDF]

, 2001

core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

First confirmation of <i>Brachycladium atlanticum</i> as aetiological agent of pulmonary pathologies in a common dolphin (<i>Delphinus delphis</i>). [PDF]

Int J Parasitol Parasites Wildl
Estarrona A, Peñín G, Lekube X, Valenciano I, Díaz de Cerio O, Soto M, Izagirre U, Benito D.   +7 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Morphological and Molecular Studies of Tetracotyle-Type Metacercariae of the Genus <i>Cotylurus</i> Szidat, 1928 (Trematoda) from the Gravel Snail <i>Lithoglyphus naticoides</i> (Gastropoda) and Host Sex Dependent Differences in Infection Rate. [PDF]

Pathogens
Stanevičiūtė G, Stunžėnas V, Petkevičiūtė R.   +2 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source